Wegovy Pill UK: What It Is, How to Take It and What to Expect (November 2026)

01 · Is it for you

Is the Wegovy pill right for you?

Wegovy tablets are licensed for weight management in adults with a BMI of 30 or above, or 27 to under 30 with at least one weight-related condition, alongside a reduced-calorie diet and more physical activity.¹ They may suit you if you would rather not inject and can take a tablet first thing every morning, then wait 30 minutes before eating or drinking. If a weekly routine suits you better, the Wegovy injection contains the same medicine.

02 · How to order

How to order Wegovy tablets

Choose Wegovy tablets, complete the free consultation, and a GPhC-registered prescriber reviews it. If approved, our pharmacy sends your tablets with free next-day tracked delivery; if not, your order is refunded automatically in full. Our Wegovy pill price page explains the cost. Wegovy tablets are a prescription-only medicine, supplied only after an online consultation reviewed by a GPhC-registered prescriber. Individual results vary. This page is information, not a substitute for medical advice.

03 · What the Wegovy pill is

What is the Wegovy pill?

Wegovy tablets contain semaglutide, the same medicine as the Wegovy injection, which acts on the GLP-1 receptor to reduce appetite and slow stomach emptying.¹ Two GLP-1 weight-loss tablets are now licensed in the UK: Wegovy tablets (oral semaglutide, made by Novo Nordisk), approved by the MHRA in June 2026, and Foundayo (orforglipron, made by Eli Lilly), approved in August 2026.²³

Because a tablet has to be absorbed from the stomach, the tablet doses are much higher in milligrams than the injection doses. The numbers simply reflect how much medicine each route needs.

04 · How to take it

How to take the Wegovy pill

The tablet must be taken on an empty stomach after fasting for at least 8 hours, swallowed whole with a sip of water (up to half a glass, about 120ml), and you then wait at least 30 minutes before eating, drinking or taking other tablets.¹ Most people take it first thing in the morning. If a dose is missed, skip it and take the next tablet the following day.

05 · Doses

Wegovy pill doses

Treatment starts at 1.5mg once daily and steps up to 4mg, 9mg and then the 25mg maintenance dose, with at least one month at each dose; the dose can stay at an earlier step if needed.¹

The months shown are the earliest possible. The prescriber decides each step.

06 · Results

Wegovy pill results

In the OASIS 4 trial, adults taking semaglutide 25mg tablets for 64 weeks lost on average 13.6% of their body weight, compared with 2.2% on placebo.⁴ For comparison, adults on the 2.4mg weekly injection lost on average 14.9% over 68 weeks in STEP 1.⁵ The trials were separate, so small differences should not be over-read. Our Wegovy pill vs injection guide compares the two.

07 · Side effects

Wegovy pill side effects

Side effects are similar to the injection because the medicine is the same. The most common are digestive: nausea, diarrhoea, vomiting, constipation, indigestion and stomach pain, most likely in the first weeks and after each dose increase.¹ Seek urgent medical help for severe, persistent stomach pain that may spread to your back, or signs of a severe allergic reaction. Our Wegovy side effects guide covers what helps.

08 · Switching from the injection

Switching from the Wegovy injection

People on the 2.4mg weekly Wegovy injection can move to the 25mg tablet, starting one week after their last injection.¹ If you are on a lower injection dose, the prescriber decides when to switch and which dose to start on. Never take the tablet and the injection together.

09 · Other tablets

Other weight loss tablets

In the ATTAIN-1 trial, people taking the highest dose of orforglipron (Foundayo) for 72 weeks lost on average 12.4% of their body weight, compared with 0.9% on placebo.⁶ Orlistat works differently, by blocking some fat absorption. Our guide to the best weight loss pills compares the options.