Which Should You Buy: Orlistat or Xenical?
Orlistat vs Xenical: The Clinical Facts
When deciding when to take Orlistat capsules, many patients wonder whether to choose generic Orlistat 120mg or branded Xenical 120mg. The clinical answer is straightforward: both contain exactly the same active ingredient (orlistat) at identical 120mg doses. This means both work identically in your body, blocking approximately one third of dietary fat absorption when taken with meals containing fat.
The timing remains the same for both: one capsule taken with each main meal containing fat, up to three times daily. Whether you choose Orlistat or Xenical, you'll take your capsule immediately before, during, or up to one hour after eating.
The Key Difference: Price Comparison
While clinically equivalent, the cost difference is significant. At EverydayMeds, generic Orlistat 120mg costs £32.99 for 84 capsules (4-week supply), reduced to £29.69 with discount code EDM10. Branded Xenical 120mg costs £42.99 for the same quantity, reduced to £38.69 with EDM10. That's a monthly saving of £9 when choosing generic Orlistat.
For longer treatment periods, savings increase further. A 12-week supply of Orlistat costs £86.39 (with EDM10) compared to £116.09 for Xenical - saving £29.70 over three months whilst receiving identical clinical benefits.
When to Choose Generic Orlistat
Generic Orlistat 120mg capsules offer excellent value without compromising effectiveness. Following clinical assessment by our UK-licensed prescribers, many patients choose generic Orlistat because it delivers the same fat-blocking action as Xenical at a lower cost. The capsules work by inhibiting lipase enzymes in your gut, preventing approximately one third of dietary fat from being absorbed.
Available pack sizes include 42 capsules (2 weeks, £15.20 with EDM10), 84 capsules (4 weeks, £29.69 with EDM10), 168 capsules (8 weeks, £57.59 with EDM10), and 252 capsules (12 weeks, £86.39 with EDM10).
When to Choose Branded Xenical
Some patients prefer branded Xenical 120mg, manufactured by Roche. While more expensive, Xenical may appeal to those who prefer established branded medications. The clinical effect remains identical to generic Orlistat - both block the same proportion of dietary fat when taken correctly with reduced-calorie, lower-fat meals.
Xenical pricing starts from £19.35 for 42 capsules (with EDM10), with larger packs offering better value per capsule despite the brand premium over generic alternatives.
Alternative Option: Alli 60mg
For those seeking a lower-strength option, Alli 60mg capsules provide half the dose of prescription-strength orlistat. While less potent than both Orlistat 120mg and Xenical 120mg, Alli may suit patients preferring a gentler starting approach. Priced from £26.09 for 4 weeks (with EDM10), Alli blocks a smaller proportion of dietary fat with typically milder side effects.
Professional Online Prescription Service
Both Orlistat and Xenical require prescription following clinical assessment. Our online consultation process involves completing a medical questionnaire reviewed by UK-licensed prescribers. Where clinically appropriate, prescriptions are issued and medications dispensed by our GPhC-registered Leicester pharmacy.
Next-day delivery is available across the UK, with discrete packaging ensuring privacy. Code EDM10 provides 10% off every order for both new and returning customers, making treatment more affordable regardless of your choice between Orlistat and Xenical.


