Which Should You Buy: Orlistat or Xenical?
Orlistat vs Xenical: The Key Facts
Both orlistat 120mg and Xenical 120mg contain identical active ingredients at the same dose. They work by blocking approximately one third of dietary fat absorption in your gut, supporting weight management alongside a reduced-calorie, lower-fat diet. The clinical effect is identical — the main difference is cost.
Generic Orlistat 120mg: Best Value Option
Generic orlistat offers the same clinical benefits as branded Xenical at a lower price. Our 4-week supply (84 capsules) costs £32.99, or just £29.69 with code EDM10. For 12-week treatment, you'll pay £95.99 (£86.39 with EDM10). Manufactured by licensed generic pharmaceutical companies, orlistat 120mg is clinically equivalent to Xenical but costs approximately £9 less per month.
Branded Xenical 120mg: The Original
Xenical is the original branded orlistat manufactured by Roche. Some patients prefer the branded option for familiarity or personal preference. Our Xenical pricing: 4-week supply £42.99 (£38.69 with EDM10), 12-week supply £128.99 (£116.09 with EDM10). Both orlistat and Xenical require the same online clinical assessment and prescription approval.
Alli 60mg: Lower-Strength Alternative
Alli contains 60mg orlistat — half the prescription dose. This lower-strength option may suit those preferring a gentler starting point. Alli 4-week supply costs £28.99 (£26.09 with EDM10). However, clinical studies show 120mg orlistat is more effective for weight management when used alongside appropriate dietary changes.
How Both Products Work
Whether you choose generic orlistat or branded Xenical, the mechanism is identical. Both inhibit lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. Unabsorbed fat passes naturally through your body. Take one 120mg capsule three times daily with each main meal containing fat. Effects work best when combined with meals containing no more than 15g fat each.
Online Prescription Process
Both orlistat and Xenical require prescription-only access through clinical assessment. Complete our online health questionnaire covering your medical history, current medications, and BMI. Our UK-licensed prescribers review every application individually. If clinically appropriate, your prescription is dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly to your address with next day delivery.
Which Option Should You Choose?
Choose generic orlistat 120mg for maximum value — identical clinical effect at lower cost. Choose Xenical 120mg if you prefer the original branded version. Both options require the same clinical assessment and offer identical weight management support when used alongside a reduced-calorie, lower-fat diet and regular physical activity.


