Which Orlistat Product Should You Choose?
Orlistat vs Xenical: The Key Difference is Price
Both orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. Clinically, they work in the same way - blocking approximately one third of dietary fat absorption to support weight management alongside a reduced-calorie, lower-fat diet. The main difference is cost. Generic orlistat offers significant savings: a 12-week supply costs £86.39 (with EDM10) compared to £116.09 for Xenical - saving you almost £30.
Alli 60mg: The Lower-Strength Alternative
Alli contains orlistat at half the prescription strength (60mg vs 120mg). While less potent than prescription orlistat or Xenical, it may suit those preferring a gentler starting approach. Alli 60mg costs £26.09 for a 4-week supply with EDM10. However, prescription-strength orlistat 120mg offers better value - a 4-week supply costs just £29.69 with significantly higher potency.
How All Three Products Work
Whether you choose orlistat, Xenical, or Alli, the mechanism remains the same. Orlistat inhibits lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body, reducing calorie intake from fat. All products must be used alongside a reduced-calorie, lower-fat diet and regular physical activity for effective weight management.
Our Pricing Comparison
Orlistat 120mg: 2-week supply £15.20, 4-week supply £29.69, 8-week supply £57.59, 12-week supply £86.39 (all with EDM10). Xenical 120mg: 2-week supply £19.35, 4-week supply £38.69, 8-week supply £78.29, 12-week supply £116.09 (with EDM10). Alli 60mg: 4-week supply £26.09, 8-week supply £49.49, 12-week supply £116.99 (with EDM10). Use code EDM10 for 10% off every order.
Making Your Decision
Choose generic orlistat 120mg for maximum value and full prescription strength. Opt for Xenical 120mg if you prefer the branded option - clinical effects are identical to generic orlistat. Consider Alli 60mg only if you specifically want lower-strength orlistat, though prescription-strength options offer better value per mg of active ingredient.
Order Process
All orlistat products require clinical assessment. Complete our online health questionnaire for review by a UK-licensed prescriber. If treatment is appropriate, your prescription will be dispensed by our GPhC-registered pharmacy and dispatched for next day delivery. Prescription costs are included - no separate GP appointment needed.


