Compare Orlistat vs Xenical: Find Your Best Option
Orlistat vs Xenical: What's the Difference?
When choosing between Orlistat 120mg and Xenical 120mg, the key difference is cost rather than clinical effect. Both contain the same active ingredient - orlistat 120mg - which works by blocking approximately one third of dietary fat absorption. Generic Orlistat costs £32.99 for 4 weeks (£29.69 with EDM10), whilst branded Xenical costs £42.99 (£38.69 with EDM10), saving you around £9 monthly with the generic option.
How Both Medications Work
Orlistat and Xenical work identically in your digestive system by inhibiting lipase enzymes that break down dietary fat. This means approximately one third of fat from meals passes through your body unabsorbed. Both require the same dosing - one 120mg capsule with each main meal containing fat, up to three times daily. The unabsorbed fat is eliminated naturally, supporting weight management when combined with a reduced-calorie, lower-fat diet.
Buy Orlistat Online - Best Value Option
Generic Orlistat 120mg offers the most cost-effective choice for prescription weight management. Our pricing starts at £16.89 for 2 weeks, with significant savings on longer supplies: 8 weeks costs £63.99 (£57.59 with EDM10) and 12 weeks £95.99 (£86.39 with EDM10). Following an online clinical assessment by our UK-licensed prescribers, suitable patients can access Orlistat without a separate GP appointment.
Buy Xenical Online - Branded Option
Some patients prefer branded Xenical 120mg, manufactured by Roche. Whilst more expensive at £42.99 for 4 weeks, it provides the same clinical benefit as generic Orlistat. Xenical pricing includes £86.99 for 8 weeks (£78.29 with EDM10) and £128.99 for 12 weeks (£116.09 with EDM10). Both options are dispensed from our GPhC-registered pharmacy following prescriber approval.
Consider Alli 60mg - Lower Strength Alternative
Alli contains orlistat at half the prescription strength (60mg). Whilst less potent than 120mg options, it may suit those preferring a gentler starting approach. Alli costs £28.99 for 4 weeks (£26.09 with EDM10) and doesn't require a prescription. However, the lower dose means reduced fat-blocking effect compared to prescription-strength Orlistat or Xenical.
Your Online Prescription Process
Getting your chosen medication is straightforward: complete our online health questionnaire covering your medical history, current medications, and weight management goals. Our UK-licensed prescriber reviews your information and issues a prescription where clinically appropriate. We then dispense and dispatch your medication with next day delivery available. The prescription is included in the price - no separate consultation fees.
Start Your Treatment Today
Ready to begin your weight management journey? Whether you choose cost-effective Orlistat, branded Xenical, or lower-strength Alli, our regulated online service makes access simple. All patients benefit from our 10% discount with code EDM10, applied to every order. Complete your clinical assessment now to discover which option your prescriber recommends for your individual circumstances.


