Choose Your Prescription Weight Loss Treatment
Prescription Orlistat for Weight Loss UK
Orlistat tablets offer clinically-studied prescription weight loss support for adults with obesity or excess weight. This lipase inhibitor works in your digestive system to block approximately one third of dietary fat from being absorbed, supporting weight management when combined with a reduced-calorie, lower-fat diet and increased physical activity.
Three Prescription Options Available
Generic Orlistat 120mg - Our most cost-effective prescription option. 4-week supply from £32.99 (£29.69 with EDM10). Clinically identical to branded alternatives.
Xenical 120mg - The original branded version by Roche. Same active ingredient and strength as generic orlistat. 4-week supply from £42.99 (£38.69 with EDM10).
Alli 60mg - Lower-strength option at half the prescription dose. 4-week supply from £28.99 (£26.09 with EDM10). Typically produces milder side effects.
How Orlistat Supports Weight Loss
Orlistat works by inhibiting lipase enzymes in your gut that break down dietary fat. When these enzymes are blocked, approximately one third of the fat you eat cannot be digested or absorbed. This unabsorbed fat passes naturally through your digestive system, helping reduce calorie intake from dietary sources.
The medication works best when you keep each meal to approximately 15g of fat or less. Higher-fat meals increase the likelihood of gastrointestinal side effects, while lower-fat meals help minimise these effects whilst allowing the medication to work effectively.
UK Online Prescription Process
Getting prescription orlistat through EverydayMeds is straightforward. Complete our online health questionnaire covering your medical history, current medications, and weight management goals. A UK-licensed prescriber reviews your information and issues a prescription where clinically appropriate. Your medication is then dispensed by our GPhC-registered pharmacy in Leicester and dispatched for next-day delivery.
This regulated process replaces the need for a face-to-face GP appointment whilst maintaining the same clinical standards. All prescriptions are subject to individual assessment - not everyone will be suitable for orlistat treatment.
Who May Be Suitable for Prescription Orlistat
Orlistat may be prescribed for adults with a BMI of 30kg/m² or above, or those with a BMI of 28kg/m² or above who have weight-related health conditions such as type 2 diabetes, high blood pressure, or elevated cholesterol. Your prescriber assesses eligibility based on your individual health circumstances during the online consultation.
Managing Treatment Effectively
Success with orlistat depends on combining the medication with sustainable lifestyle changes. Follow a reduced-calorie diet with no more than 30% of calories from fat, spread evenly across three main meals. Take one capsule with each main meal containing fat, up to three capsules daily.
Most patients experience some gastrointestinal side effects initially, particularly if eating high-fat meals. These effects often reduce as you adapt your diet to lower fat content. A daily multivitamin taken at bedtime is recommended, as orlistat may reduce absorption of fat-soluble vitamins.
Save 10% on Every Order
Use code EDM10 at checkout for 10% off all orlistat products - available for new and returning customers. This brings our 12-week generic orlistat supply down to just £86.39, offering significant savings compared to high-street options. Order now for next-day delivery across the UK.


