Why Choose Prescription Orlistat for Weight Loss?
How Orlistat 60mg and 120mg Support Weight Management
Orlistat works differently from appetite suppressants by acting locally in your digestive system. It inhibits lipase enzymes responsible for breaking down dietary fat, preventing approximately one third of the fat you eat from being absorbed. This unabsorbed fat passes naturally through your body, which may help reduce your calorie intake from dietary fat when combined with a reduced-calorie, lower-fat diet and increased physical activity.
Prescription Orlistat Options Available
We offer three clinically effective options: generic orlistat 120mg (prescription-only, from £29.69 for 4 weeks with EDM10), branded Xenical 120mg (£38.69 for 4 weeks with EDM10), and Alli 60mg (lower-strength option, £26.09 for 4 weeks with EDM10). All contain the same active ingredient but at different strengths. Orlistat 120mg and Xenical 120mg are clinically equivalent - the key difference is cost, with generic orlistat offering significant savings.
Who May Be Suitable for Orlistat Treatment
Orlistat may be suitable for adults with a BMI of 30kg/m² or above, or 28kg/m² or above with weight-related health conditions such as type 2 diabetes or high blood pressure. Treatment suitability is assessed on an individual basis following an online clinical assessment by our UK-licensed prescribers. The assessment considers your medical history, current medications, and weight management goals to determine if orlistat is right for you.
Your Online Prescription Journey
Our streamlined process makes accessing prescription weight loss treatment convenient and confidential. Complete our online health questionnaire, which is reviewed by a qualified UK-licensed prescriber. If treatment is appropriate, your prescription is issued and dispensed by our GPhC-registered pharmacy in Leicester. Orders are delivered discreetly with next-day tracked delivery across the UK. Use code EDM10 for 10% off every order, including returning customers.
Maximising Your Weight Loss Success
Orlistat works best when combined with a structured approach to weight management. Keep your daily fat intake to approximately 30% of calories, spread evenly across three main meals (roughly 15g fat per meal). This not only supports the medication's effectiveness but also helps minimise gastrointestinal side effects. Consider taking a daily multivitamin at bedtime, as orlistat may reduce absorption of fat-soluble vitamins A, D, E, and K.
Pricing and Pack Sizes
Choose from flexible supply options to suit your weight management timeline. Orlistat 120mg is available in 2-week (£15.20), 4-week (£29.69), 8-week (£57.59), and 12-week (£86.39) supplies with EDM10. Xenical 120mg offers the same clinical effect with branded assurance, while Alli 60mg provides a lower-strength starting option. All prices include the prescription and clinical assessment - no separate GP fees required.


