Detailed Comparison: Viagra, Sildenafil & Spedra
How Viagra and Spedra Work
Both Viagra (sildenafil) and Spedra (avanafil) are PDE5 inhibitors that work by blocking the phosphodiesterase type 5 enzyme. This increases blood flow to the penis when sexually aroused, helping men achieve and maintain an erection suitable for sexual activity. Neither medication causes automatic erections - sexual stimulation remains necessary for effectiveness.
Speed of Action and Duration
One key difference when comparing these treatments is onset time. Viagra typically takes 30-60 minutes to become effective, whilst Spedra can work within 15-30 minutes of taking. This faster onset makes Spedra appealing for spontaneous intimacy. However, Viagra's effects can last 4-6 hours compared to Spedra's similar duration of 4-6 hours.
Food Interactions and Convenience
Viagra's effectiveness can be reduced when taken with fatty meals, which may delay absorption. Spedra is less affected by food, making it more convenient for those who prefer not to plan around meals. This flexibility can be important for maintaining spontaneity in relationships.
Dosage Options Available
Viagra comes in 25mg, 50mg, and 100mg strengths, with 50mg being the typical starting dose. Spedra is available in 50mg, 100mg, and 200mg tablets, with 100mg as the standard initial dose. Both medications should only be taken once per 24-hour period, approximately 30-60 minutes before sexual activity.
Cost Considerations: Branded vs Generic
When looking to order Viagra on the internet, cost is often a significant factor. Branded Viagra is typically more expensive than generic sildenafil, despite containing the same active ingredient. At EverydayMeds, patients can choose between branded Viagra or generic sildenafil at checkout, with the generic option offering substantial savings whilst maintaining identical effectiveness.
Side Effects and Tolerability
Both medications share similar side effect profiles, including potential headaches, flushing, nasal congestion, and indigestion. Some men may find one medication more tolerable than the other. Spedra may have slightly fewer visual disturbances compared to sildenafil, though serious side effects remain rare with both treatments.
Eligibility and Contraindications
Both medications require prescription following consultation with a UK-licensed prescriber. Neither should be taken by men using nitrate medications for chest pain, those with severe heart conditions, or recent stroke/heart attack history. Our online clinical assessment evaluates suitability for either treatment based on medical history and current medications.
Making Your Choice
The decision between Viagra/sildenafil and Spedra often depends on individual preferences and circumstances. Men prioritising faster onset may prefer Spedra, whilst those seeking cost-effective treatment might choose generic sildenafil. Both are clinically proven treatments with excellent safety profiles when used appropriately under medical supervision.












