Tirzepatide Weight Loss Injections in Encino: What UK Readers Need to Know (October 2026)

01 · Where you are matters

Encino clinics versus a UK online pharmacy

Encino is a neighbourhood of Los Angeles, and local medical spas and wellness centres there supply under US rules, with US pricing and US prescribers. We are a different thing: a GPhC-registered UK online pharmacy (registration 9012878) that supplies UK customers. If you are physically in California, a local licensed US provider is the route that applies to you.

The medicine is the same active ingredient, tirzepatide, sold in the UK under the brand name Mounjaro. It is a once-weekly injection licensed here for weight management in adults and for type 2 diabetes.¹ You can read our wider overview of weight loss injections or see all weight loss treatments we dispense.

02 · Cost

What Mounjaro costs in the UK

The standard price of one Mounjaro pen, which is four weeks of weekly doses, is £169.99 at 2.5mg, £218.99 at 5mg, £279.99 at 7.5mg, £290.99 at 10mg, £319.99 at 12.5mg and £329.99 at 15mg. Those are monthly pen prices. You can see them live, with ordering, on the Mounjaro pen page.

A new customer gets £40 off their first order at any dose with code FIRST40. That includes people switching to us from another provider at a higher dose. Your first 2.5mg pen is therefore £129.99, and switching at 15mg, your first order is £289.99. After that, every later order is £25 off the standard price through the automatic reorder discount (code DOSE25).

Across the UK pharmacies we track, Mounjaro pens ranged from £143.96 to £339.00 per month across all doses when we checked on 10 October 2026. For the 2.5mg starting pen alone the range was £143.96 to £179.99, and the gap between providers for the same dose ran from £27 to £41. Boots' Mounjaro prices ran from £179.00 to £339.00. We show those figures so you can compare like for like.

03 · What you get

What the price includes

The consultation is free, and the price shown is the price paid, with no hidden fees. Needles, a sharps bin and injection guidance come with every order. Ongoing monthly clinical reviews, dose-titration support and side-effect support are part of our aftercare. We supply genuine KwikPens through official LillyDirect supply, sourced directly from Eli Lilly's UK distribution, and all six doses are in stock.

Delivery is free, next-day and tracked, using DPD in temperature-controlled, discreet packaging. Orders placed by 3pm are dispatched the same day. Saturday delivery is £14.99. You can pay by Visa or Mastercard, with Klarna and pay-monthly options, and there is no subscription lock-in. Repeat orders re-check suitability, and nothing ships automatically. If you want to see how delivery works in detail, read about tirzepatide next-day delivery.

04 · Ordering

How ordering works in three steps

First, complete the short online health questionnaire. The consultation is free, with no obligation, and you can start your free consultation here. Second, a GPhC-registered prescriber reviews your answers. This is a clinical review, not a scoring script. Payment is taken when you place the order; if the prescriber decides the treatment is not suitable, the order is refunded automatically in full. Third, our registered pharmacy dispenses and dispatches your pen with free next-day tracked delivery.

If you would rather set up an account first, see how to register online. Mounjaro is a prescription-only medicine, supplied only after an online consultation reviewed by a GPhC-registered prescriber.

05 · What tirzepatide is

What tirzepatide is and how it works

Tirzepatide is the active ingredient in Mounjaro, a once-weekly injectable prescription medicine made by Eli Lilly. In the UK it is licensed for weight management in adults and for type 2 diabetes. It comes as a pre-filled multi-dose pen, the KwikPen, in six strengths: 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg and 15mg.¹ Each pen contains four weekly doses, so one pen covers one month of treatment.

Tirzepatide is the generic name, and Mounjaro is the brand. In the UK, the brand product from Eli Lilly is the licensed route, supplied against a prescription after a consultation.

Tirzepatide is the first treatment of its kind to activate two natural gut-hormone receptors at once: GIP and GLP-1. Together these help regulate appetite, slow how quickly the stomach empties, and improve the way the body responds to insulin.¹ In practice, most people feel fuller sooner and less hungry between meals, which supports a reduced-calorie diet.

That dual action is what distinguishes Mounjaro from single-action GLP-1 medicines such as semaglutide, sold as Wegovy and Ozempic. Tirzepatide works differently from semaglutide, through two receptors rather than one. A prescriber can talk you through the choice.

It is worth being clear about what the injection is not. It is not a replacement for eating well or moving more. The licence says it must be used alongside a reduced-calorie diet and increased physical activity. The pen does the appetite-regulating work, while the habits you build around it decide how much of that effect is useful in daily life.

Because the medicine is a weekly injection, there is no daily routine to remember. You choose one day each week, inject under the skin, and rotate the site. Our companion app, GLPTrackr, is free on iOS and Android if you want somewhere to log doses, weight and side effects over time.

The Patient Information Leaflet that comes in every box gives the full list of possible effects and who should not use the medicine.¹³ We recommend reading it before your first injection, and keeping it for reference as you move up the doses. If anything in it worries you, raise it with your prescriber before you start rather than after.

06 · Who can use it

Who can use it: UK eligibility

Mounjaro is licensed for weight management in adults with a BMI of 30 or above, or a BMI between 27 and 30 with at least one weight-related condition. Examples include high blood pressure, high cholesterol, obstructive sleep apnoea, cardiovascular disease, prediabetes or type 2 diabetes.¹ It must be used alongside a reduced-calorie diet and increased physical activity.

That is the licensed position for private prescribing. A prescriber assesses your BMI, medical history and current medicines before deciding whether it is suitable for you. The decision is clinical and individual. Someone who meets the BMI numbers may still be advised against treatment, and the review exists to catch that.

You should not take Mounjaro if you are allergic to tirzepatide or any of its ingredients, and it should not be used during pregnancy or while trying to conceive. Your prescriber will take extra care, or may recommend against treatment, if you have a history of pancreatitis, severe gut or digestive disease, diabetic retinopathy, or gallbladder problems. Always share your full medical history and medicine list during consultation.¹³ Mounjaro must not be used during pregnancy, and it should be stopped at least one month before trying to conceive. If you become pregnant during treatment, stop the medicine and tell your prescriber promptly. Thyroid history is one example of something worth discussing, and our guide on weight loss injections and thyroid problems explains what to raise.

NHS versus private

Mounjaro is available on the NHS, but access is being phased in over several years. NICE recommends it for adults with a BMI of at least 35 plus at least one weight-related condition. The NHS primary-care rollout began in June 2025 with the highest-need groups first, initially BMI 40 or above with four or more qualifying conditions.⁴⁶ Full rollout is expected to take years, which is why many people who meet the licensed criteria choose regulated private treatment rather than waiting.

The NHS threshold is narrower than the licence. If you sit at a BMI of 30 to 35, or between 27 and 30 with a weight-related condition, you may meet the licensed criteria without being in an early NHS group. Ask your GP where you fall in the current rollout.

Why the consultation matters

The consultation is where eligibility is actually decided. It is free, with no obligation, and payment is taken when you place the order. If the prescriber decides Mounjaro is not suitable, the order is refunded automatically in full. That means you do not pay for treatment the prescriber decides is not suitable.

If you are unsure which treatment fits you, the weight loss treatments overview sets out the options we dispense. Our guide Are weight loss injections safe? covers the broader risk picture in plain language and is a good read before you decide.

07 · Doses and titration

The dose ladder and first weeks

Everyone starts Mounjaro on 2.5mg once a week. This starting dose is about letting your body adjust, not about weight loss itself. After at least 4 weeks the dose increases to 5mg. It can then step up by 2.5mg at a minimum of 4-week intervals, through 7.5mg, 10mg and 12.5mg, up to a maximum of 15mg weekly, depending on how you respond and tolerate it.¹

Many people settle at a maintenance dose of 5mg, 10mg or 15mg. Higher is not automatically better, and your prescriber will guide the right pace. Settling at a dose that works for you is a clinical decision, not a race to the top.

If you step up after 4 weeks on each dose, your first four pens (2.5mg to 10mg) cost £959.96 at standard prices. That total is before discounts: a new customer's first order is £40 less, and every later order is £25 less.

What the first weeks feel like

The 2.5mg starting weeks are about adjustment, and experiences differ widely. Some people notice appetite change and early loss in week one, while others feel little until a higher dose. Both are normal. Early loss includes water weight, so the trend over weeks matters more than any single weigh-in.¹

Mild nausea, altered appetite and tiredness in the first days after each injection are the commonest early effects and usually settle. The early effects are the ones to expect and plan around. For the complete list of possible side effects, including less common ones, use the Patient Information Leaflet, and report any suspected side effect through the Yellow Card scheme.¹⁹

08 · Results to expect

What results to expect

In the SURMOUNT-1 trial of 2,539 adults, people taking tirzepatide alongside diet and exercise lost on average 15% of their body weight on 5mg, 19.5% on 10mg and 20.9% on 15mg over 72 weeks, compared with 3.1% with lifestyle changes alone.² These are trial averages. Individual results vary, and treatment works alongside a reduced-calorie diet and increased physical activity, not instead of them.

At 72 weeks, 85% of participants on 5mg, 89% on 10mg and 91% on 15mg had lost at least 5% of their body weight. Half of participants on 10mg and 57% on 15mg lost at least 20% of their body weight.² Trial averages do not predict your own result, so treat them as a picture of what the study found, not a forecast.

A worked example

To make the percentages concrete, for someone starting at 100 kg, 20.9% is about 21 kg, and 15% is about 15 kg. Those figures are straight arithmetic from the SURMOUNT-1 trial percentages, not a promise of what you will lose. You can see how the averages are plotted in our Mounjaro weight loss graph.

"How much will I lose in 2 months?"

Weight loss on Mounjaro is gradual by design. The first weeks on 2.5mg are an adjustment phase and losses are usually modest. Most measurable progress builds from 5mg onward, month by month.¹ Because the dose ladder moves up at a minimum of 4-week steps, two months usually sits within the early part of treatment. Think in months, not days, and judge progress by trend, not individual weigh-ins.

When your prescriber reviews progress

Treatment response is reviewed by your prescriber. If you have lost less than 5% of your starting weight after 6 months on the highest dose you can tolerate, your prescriber will discuss whether continuing or stopping is right for you.¹

Practical habits make the review more useful. Weigh at the same time of day, record the trend rather than reacting to single readings, and note how your appetite and side effects change as the dose moves. Our free GLPTrackr app can hold all of that in one place and makes the monthly review conversation easier, because you can show rather than recall.

Finally, remember that Mounjaro is licensed for use with a reduced-calorie diet and increased physical activity. The trial comparison group, who had lifestyle changes alone, lost 3.1% on average. The medicine moves the odds in your favour, but the daily habits are still part of the treatment.

09 · A year of costs

Planning a year of treatment

A first year of Mounjaro costs £2,711.88 if you stay on 5mg after your 2.5mg starting pen, up to £3,599.88 if you step up through every dose to 15mg. Those totals cover 52 weeks, or 13 pens, at standard prices before discounts. A new customer's first order is £40 less, and every later order is £25 less.

You start at 2.5mg and move up with at least 4 weeks on each dose, depending on how you respond. If you step up after 4 weeks on each dose, your first four pens (2.5mg to 10mg) cost £959.96 at standard prices, again before discounts.

For maintenance doses between those two, the monthly pen price applies.

How the discounts apply

The discounts are live and set in the shop. A new customer gets £40 off their first order at any dose with code FIRST40. After that, every future order gets an automatic £25 off (code DOSE25). The ongoing monthly cost at any dose is therefore that dose's standard price minus £25.

Paying your way

You can pay by Visa or Mastercard, or use Klarna and pay-monthly options. There is no subscription, so you decide each month whether to reorder, and each repeat order re-checks suitability. If your circumstances change, you are not locked into anything. You can check the live prices on the Mounjaro page any time before ordering.

10 · Injecting and storage

Injecting, missed doses and storage

Mounjaro is injected under the skin once a week, on the same day each week, at any time of day, with or without food. Licensed injection sites are the stomach area (at least 5cm from the belly button), the front of the thigh, or the back of the upper arm if someone else gives the injection. Rotate the site with each dose. Each KwikPen contains four weekly doses.¹

There is no "best" time of day. Mounjaro works the same morning or evening. What matters is the same day each week. Needles, a sharps bin and injection guidance come with every order, and the pen's own instructions are the guide to the injection itself. Follow them closely, and ask our team if anything is unclear.

Setting the dose

The KwikPen is set by turning the dose knob until the dose indicator shows the correct dose in the window.

If you miss a dose

If you miss a dose, take it as soon as you can within 4 days (96 hours) of the scheduled time, then carry on with your usual day. If more than 4 days have passed, skip the missed dose entirely and take the next one on your normal day. Never take two doses within 3 days of each other.¹ If you want to move your regular day, you can, provided at least 3 days (72 hours) have passed since your last dose.

Storage

Keep Mounjaro pens in a fridge at 2 to 8°C and never freeze them. Once in use, a pen can be kept out of the fridge not above 30°C for up to 30 days, which is useful for short trips, after which it should be discarded. Keep the pen cap on to protect it from light, and never use a pen that has been frozen.¹

Unopened pens should be kept in the fridge and keep until the expiry date printed on the box. If an unopened pen has been out of the fridge, check with the pharmacy before using it rather than relying on a remembered day limit. Figures circulating online often come from other countries' labels, and the UK label is the one that applies to a UK pen.

Travelling

You can fly with Mounjaro. Carry pens in hand luggage, because hold luggage can fall below freezing, ideally in a cool bag with the prescription label or a copy of your prescription. In-use pens tolerate up to 30 days not above 30°C, so most holidays need no special arrangements. For hot climates, use an insulated pouch. Check destination rules for travelling with prescription injectables before you fly, and that includes the United States if you are heading to California.

Our deliveries arrive in temperature-controlled packaging. On arrival, put the pen in the fridge unless you are about to use it, and check it looks as described in the leaflet.

11 · Stopping and duration

How long you can take it and what happens after

The right duration is a clinical decision made with your prescriber at regular reviews. If you have lost less than 5% of your starting weight after 6 months on the highest dose you can tolerate, your prescriber will discuss whether continuing or stopping is right for you.¹ Our aftercare includes ongoing monthly reviews, dose-titration and follow-up assessments by the prescribing team.

Trials measured results at 72 weeks, but that is the length of a study, not a limit on treatment. Whether you continue, hold your dose or stop is something you decide with your prescriber, based on how you are doing, what you tolerate, and what you want.

Does it wear off after 5 days?

No. Tirzepatide has a half-life of about five days, so after a final dose it takes roughly 4 to 5 weeks to clear the system. There is no way to speed this up, and nothing needs doing while it clears.¹ A half-life is the time for the amount in your body to fall by half, not the time for it to disappear. So after five days, about half is still there. That slow clearance is also one reason the once-weekly schedule works.

What happens after you stop

In SURMOUNT-4, people who stopped tirzepatide after 36 weeks regained on average 14% of body weight over the following year, while those who continued treatment lost a further 5.5% on average.¹⁴ Discuss your plan with your prescriber before you stop, not after, so you have a diet and activity routine ready that you can keep up without the injection.

If you stop for a while and want to restart, tell your prescriber how long you have been off. Restarting is a clinical decision, and your prescriber will decide which dose to begin at.

Switching or pausing safely

If a new dose is hard to tolerate, prescribers can hold the current dose longer before stepping up. Speak to your clinical team rather than pushing through severe symptoms. Always use one pen at a time, and throw it away 30 days after first use, or sooner if it has been above 30°C.

If you are weighing up injections against other approaches, our weight loss injections blog collects our guides, and the weight loss injections hub compares the main routes. Whatever you choose, make it with a prescriber who knows your history.

12 · Buying safely

Buying tirzepatide safely

The safest way to buy tirzepatide is from a registered pharmacy, after a consultation reviewed by a prescriber. You can check any UK pharmacy on the GPhC register. Ours is registration 9012878.¹² Mounjaro is a prescription-only medicine, so anyone offering to supply it without a consultation or prescription is a red flag.

Counterfeit and unregulated products are a real concern with high-demand medicines. The MHRA publishes counterfeit medicine alerts and runs the Yellow Card scheme for reporting suspected side effects and suspect products.⁷ If a pen looks wrong, is unlabelled, or arrives without the manufacturer's packaging, do not use it.

What our supply looks like

We supply through official LillyDirect supply, sourcing Mounjaro directly from Eli Lilly's UK distribution. These are genuine KwikPens, and all six doses from 2.5mg to 15mg are in stock. Each order is dispensed by our registered pharmacy and delivered next day, tracked, in temperature-controlled packaging.

Over 100,000 customers have been supported on their weight loss journey with us. That is a measure of how many people we have served, not a statement about what any one person will achieve.

Questions to ask any provider

Whether you are comparing providers in the UK or thinking about a local clinic abroad, a few questions are worth asking. Is the person prescribing registered with a recognised regulator? Is the product a licensed brand in its original packaging? Will someone review your suitability, including your other medicines? Who do you contact if you have side effects? Will the price you are quoted be the price you pay?

With us you get GPhC registration, genuine KwikPens, prescriber review, support Monday to Friday 9am to 5pm by email at support@everydaymeds.co.uk, through the account portal chat or by phone on 0333 207 0413, and a price that includes no hidden fees.

Refunds and returns

Orders declined at prescriber review are refunded automatically in full. Dispensed prescription medicines cannot be returned, except for a faulty, damaged or wrong item, which you should report within 3 days. Refunds take 5 to 10 working days.

Reporting matters. If you suspect a side effect or a problem with a pen, report it through the Yellow Card scheme as well as telling your prescriber.¹⁹ Reports help regulators spot patterns that no single prescriber can see. You can begin a free consultation whenever you are ready.

13 · Serious side effects

Serious side effects: when to get help straight away

Serious side effects are uncommon but need urgent attention. Seek immediate medical help for: severe, persistent stomach pain that may spread to your back, with or without vomiting (possible pancreatitis); pain in the upper right abdomen, fever or yellowing of skin/eyes (possible gallbladder problems); or signs of a severe allergic reaction such as swelling of the face or throat and difficulty breathing. If you take insulin or a sulfonylurea alongside Mounjaro, watch for low blood sugar (shakiness, sweating, confusion) — your prescriber may need to adjust those medicines.¹