Sildenafil vs Spedra: Key Differences and Similarities
How Both Medications Work
Sildenafil and Spedra both belong to a class of medications called PDE5 inhibitors. They work by blocking the phosphodiesterase type 5 enzyme, which increases blood flow to the penis during sexual arousal. Neither medication causes automatic erections - sexual stimulation is still required for both treatments to be effective.
Speed of Action
One of the main differences between these treatments is how quickly they begin working. Spedra (avanafil) may start working within 15-30 minutes, making it one of the faster-acting ED treatments available. Sildenafil typically takes 30-60 minutes to become effective, though this can vary between individuals.
Food intake can affect both medications, but Spedra may be less affected by meals compared to sildenafil. Fatty meals can particularly delay sildenafil's onset of action.
Duration of Effect
Both sildenafil and Spedra provide similar duration of effectiveness, typically lasting 4-6 hours. This doesn't mean an erection will last this long, but rather that the medication may help achieve erections during this window when sexually stimulated.
Dosage Options
Sildenafil is available in 25mg, 50mg, and 100mg strengths, with 50mg being the typical starting dose. At EverydayMeds, patients can choose between branded Viagra or generic sildenafil at checkout - both contain the same active ingredient. Spedra comes in 50mg, 100mg, and 200mg tablets, with 100mg being the standard starting dose.
Cost Considerations
Generic sildenafil offers significant cost savings compared to Spedra whilst providing the same proven effectiveness. This makes sildenafil particularly attractive for men seeking long-term ED treatment. Even branded Viagra may be more cost-effective than Spedra for many patients.
Clinical Evidence and Experience
Sildenafil has over 25 years of clinical use and extensive research data supporting its safety and effectiveness. It was the first oral PDE5 inhibitor approved for ED treatment. Spedra, whilst newer, also has strong clinical trial data showing its effectiveness.
Side Effects Profile
Both medications may cause similar side effects, including headaches, facial flushing, indigestion, and nasal congestion. Some users report that Spedra may have fewer side effects, though individual responses vary considerably. Both are generally well-tolerated when used appropriately under medical supervision.
Which Treatment Might Suit You?
The choice between sildenafil and Spedra often depends on individual priorities. If faster onset is important and cost isn't a primary concern, Spedra might be preferred. For those seeking proven effectiveness at lower cost, sildenafil represents excellent value.
At EverydayMeds, our UK-licensed prescribers can help determine which treatment may be most suitable based on your medical history, current medications, and personal preferences during your online consultation.
