Xenical vs Alli: UK Prescription Weight Loss Comparison

pricing for mounjaro and wegovy weight loss

Choosing between prescription weight loss treatments in the UK? Compare Xenical 120mg, generic orlistat 120mg, and Alli 60mg. All work by blocking approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet. Generic orlistat 120mg starts from £32.99 for 4 weeks (£29.69 with code EDM10), Xenical from £42.99, and Alli 60mg from £28.99. Following online clinical assessment by UK-licensed prescribers, dispensed by our GPhC-registered Leicester pharmacy with next-day delivery. Get 10% off every order with EDM10.

  • Same active ingredient in Xenical and orlistat 120mg - significant cost savings with generic
  • Online prescription service - no GP appointment needed, reviewed by UK-licensed prescribers
  • Next-day delivery from GPhC-registered pharmacy in Leicester with discreet packaging
  • 10% off every order with code EDM10 - new and returning customers eligible
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Compare Prices: Orlistat vs Xenical vs Alli UK

Reviewed by Mostafa Damghani · 03/07/2026

Xenical vs Orlistat 120mg: Same Effect, Different Price

Both Xenical 120mg and generic orlistat 120mg contain identical active ingredients at the same dose. They work by blocking approximately one third of dietary fat absorption in your gut, supporting weight management when used alongside a reduced-calorie, lower-fat diet. The key difference is cost - generic orlistat 120mg costs £32.99 for 4 weeks (£29.69 with EDM10), whilst branded Xenical costs £42.99 for the same period. This represents savings of approximately £9 per month when choosing the generic option.

Alli 60mg: Lower Strength Alternative

Alli contains half the dose of prescription-strength orlistat at 60mg per capsule. This lower strength may be suitable for those preferring to start with a gentler approach, though it blocks a smaller proportion of dietary fat compared to the 120mg prescription options. Alli 60mg costs £28.99 for 4 weeks (£26.09 with code EDM10) and doesn't require a prescription, though clinical assessment is still recommended.

Treatment Duration and Pack Sizes

All three options are available in multiple pack sizes to suit different treatment durations. Generic orlistat 120mg offers the best value for longer treatment courses - 12 weeks costs £95.99 (£86.39 with EDM10). Xenical 120mg for 12 weeks costs £128.99 (£116.09 with EDM10). Treatment duration should be determined following consultation with a healthcare professional as part of a comprehensive weight management programme.

How All Three Products Work

Orlistat works by inhibiting lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body. This mechanism is identical whether you choose generic orlistat 120mg, branded Xenical 120mg, or lower-strength Alli 60mg. All work best when combined with meals containing no more than 15g fat per meal to minimise gastrointestinal side effects.

UK Online Prescription Process

For 120mg prescription options, complete our online health questionnaire covering your medical history, current medications, and weight management goals. A UK-licensed prescriber reviews your information and issues a prescription where clinically appropriate. Your medication is then dispensed by our GPhC-registered pharmacy in Leicester and dispatched with next-day delivery. Use code EDM10 for 10% off your order.

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Once you complete a short online assessment, you’ll be able to choose your preferred treatment and quantity from a list of safe, medically approved options tailored to you.

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FAQs

Frequently asked questions

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What's the main difference between Xenical and generic orlistat 120mg?
Both contain identical active ingredients at the same 120mg dose with the same clinical effect. The key difference is cost - generic orlistat saves approximately £9 per month compared to branded Xenical. Complete our online assessment to access either option.
How much can I save by choosing generic orlistat over Xenical?
Generic orlistat 120mg costs £29.69 for 4 weeks with code EDM10, whilst Xenical costs £38.69 for the same period - saving you £9 monthly. For 12-week supplies, you save approximately £30 by choosing generic.
Do I need a prescription for all these weight loss treatments?
Orlistat 120mg and Xenical 120mg require prescriptions following clinical assessment. Alli 60mg doesn't require a prescription but clinical guidance is recommended. Complete our online consultation for professional review of your suitability.
Are these treatments regulated and safe to buy online?
Yes, all our medications are dispensed by a GPhC-registered pharmacy in Leicester, prescribed by UK-licensed healthcare professionals, and sourced through MHRA-regulated supply chains. We follow the same legal standards as traditional pharmacies.
How quickly can I receive my weight loss medication?
Following prescriber approval, we dispatch orders the same day with next-day delivery across the UK. Your medication arrives in discreet, secure packaging with tracking information provided.