Safe Prescription Weight Loss with Sertraline
Taking Orlistat with Sertraline Safely
Many patients successfully use orlistat for weight management whilst taking sertraline for depression or anxiety. During your online clinical assessment, our UK-licensed prescribers carefully review all current medications including sertraline to ensure safe prescribing. Orlistat works locally in the gut by blocking approximately one third of dietary fat absorption, whilst sertraline acts on brain chemistry - these different mechanisms mean they can typically be prescribed together when clinically appropriate.
Prescription Weight Loss Options
We offer three prescription weight loss options following clinical assessment. Generic orlistat 120mg provides excellent value from £15.20 for 2 weeks (£16.89 before EDM10 discount). Branded Xenical 120mg contains the same active ingredient from £19.35 for 2 weeks (£21.50 before discount). Alli 60mg offers a lower-strength option from £26.09 for 4 weeks. All options may help reduce dietary fat absorption when used alongside a reduced-calorie, lower-fat diet.
How Orlistat Supports Weight Management
Orlistat capsules work by inhibiting lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body, potentially reducing calorie intake from fat. The medication works best when combined with meals containing no more than 15g fat per meal. Our prescribers provide dietary guidance alongside your prescription to maximise effectiveness whilst minimising gastrointestinal side effects.
Professional Clinical Assessment
Your online consultation covers medical history, current medications including sertraline, BMI calculation, and weight management goals. Our UK-licensed prescribers assess whether orlistat is suitable alongside your existing treatment. The assessment typically takes 24 hours, with approved prescriptions dispensed immediately by our GPhC-registered pharmacy in Leicester. Prescription costs are included - no separate GP appointment required.
Convenient UK Delivery
All orders receive next day tracked delivery in discreet packaging. Choose from multiple pack sizes: 2-week supply (42 capsules), 4-week supply (84 capsules), 8-week supply (168 capsules), or 12-week supply (252 capsules). Remember to use code EDM10 for 10% off every order - available for new and returning customers. Complete your consultation today to start your supervised weight loss journey.


