Compare Your Prescription Weight Loss Options
Orlistat vs Wegovy: Understanding Your Options
When considering prescription weight loss treatments, orlistat offers a well-established option that works differently from newer injectable treatments. Orlistat works locally in the gut by blocking approximately one third of dietary fat absorption, whilst treatments like Wegovy act as appetite suppressants. Following clinical assessment, orlistat may be suitable for adults with a BMI of 30 kg/m² or above, or 28 kg/m² with weight-related health conditions like type 2 diabetes or high blood pressure.
Orlistat 120mg: Cost-Effective Generic Option
Generic orlistat 120mg provides the most affordable prescription weight loss option. At £32.99 for a 4-week supply (£29.69 with EDM10), it offers excellent value whilst delivering the same clinical effect as branded alternatives. Each pack contains 84 capsules for one month of treatment, taken three times daily with main meals containing fat. Our 8-week supply at £63.99 (£57.59 with EDM10) provides better value for ongoing treatment.
Xenical 120mg: Trusted Branded Treatment
Xenical contains identical orlistat 120mg but as the original branded version by Roche. Priced at £42.99 for 4 weeks (£38.69 with EDM10), some patients prefer the branded option for peace of mind. Both generic orlistat and Xenical work identically - inhibiting lipase enzymes to reduce dietary fat absorption by approximately one third. Choose based on personal preference and budget, as clinical effectiveness remains the same.
Alli 60mg: Lower-Strength Alternative
Alli provides half the strength at 60mg per capsule, offering a gentler introduction to orlistat treatment. At £28.99 for 4 weeks (£26.09 with EDM10), Alli may suit those preferring to start with lower-dose treatment. Whilst clinically less potent than 120mg options, Alli can still support weight management alongside dietary changes, typically with milder gastrointestinal side effects due to the reduced dose.
How Orlistat Supports Weight Management
Orlistat works by blocking approximately one third of dietary fat from being absorbed in the gut. Unlike appetite suppressants that affect the brain, orlistat acts locally in the digestive system. The unabsorbed fat passes naturally through the body, potentially reducing calorie intake when combined with a reduced-calorie, lower-fat diet. Treatment works best when fat intake is kept low - approximately 15g per main meal - which also helps minimise side effects like oily stools or urgent bowel movements.
Starting Your Prescription Weight Loss Journey
All orlistat treatments require clinical assessment before prescription. Complete our online health questionnaire covering your medical history, current medications, and weight management goals. A UK-licensed prescriber reviews your information and, if clinically appropriate, issues a prescription. Choose from our range: 2-week starter packs, 4-week supplies, or 12-week courses up to £128.99 for Xenical (£116.09 with EDM10). All orders include next-day delivery and are dispensed by our GPhC-registered pharmacy in Leicester.
