Choose Your Orlistat Weight Loss Treatment Option
How Orlistat, Xenical and Alli Support Weight Loss
Orlistat works by blocking approximately one third of the fat you eat from being absorbed in your digestive system. Available as generic orlistat 120mg, branded Xenical 120mg, or lower-strength Alli 60mg capsules, this prescription weight loss treatment acts locally in the gut by inhibiting lipase enzymes. The unabsorbed fat passes naturally through your body, which may help reduce calorie intake when used alongside a reduced-calorie, lower-fat diet and increased physical activity.
Orlistat 120mg - Best Value Weight Loss Treatment
Our generic orlistat 120mg capsules offer the most cost-effective prescription weight loss option. Available from £15.20 for a 2-week supply (42 capsules) with EDM10 discount, or £86.39 for a 12-week course (252 capsules). Each capsule contains the same active ingredient as branded Xenical at a fraction of the cost. Take one capsule three times daily with meals containing fat. Order orlistat 120mg online following clinical assessment by our UK-licensed prescribers.
Xenical 120mg - Branded Orlistat Option
Xenical by Roche contains identical orlistat 120mg to the generic version but comes as the original branded formulation. Starting from £19.35 for 42 capsules (2-week supply) with EDM10, or £116.09 for 252 capsules (12-week course). Some patients prefer the branded option for peace of mind, whilst others choose generic orlistat for better value. Both have identical clinical effects and are prescribed following the same assessment process.
Alli 60mg - Lower Strength Alternative
Alli contains half the dose of prescription-strength orlistat at 60mg per capsule. This lower-strength option may help those who prefer starting with a gentler approach. Priced from £26.09 for 42 capsules (4-week supply) with EDM10 discount. Alli works using the same fat-blocking mechanism but with typically milder gastrointestinal effects due to the reduced dose.
Who May Be Suitable for Orlistat Treatment
Orlistat may be prescribed for adults with a BMI of 30 kg/m² or above, or BMI 28 kg/m² or above with weight-related health conditions such as type 2 diabetes or high blood pressure. Treatment suitability is assessed individually by our UK-licensed prescribers through an online clinical consultation. The assessment considers your medical history, current medications, and weight management goals to determine if prescription weight loss treatment is appropriate.
Online Prescription Process
Complete our confidential health questionnaire covering your medical history, current weight, and previous weight loss attempts. A qualified UK prescriber reviews your information and issues a prescription where clinically appropriate. Your treatment is then dispensed by our GPhC-registered Leicester pharmacy and dispatched for next day delivery. The prescription consultation is included in the price - no separate GP appointment required.
Managing Treatment Effectively
Orlistat works best when combined with a structured approach to diet and exercise. Keep your fat intake to approximately 15g per meal to minimise gastrointestinal side effects whilst maximising the medicine's effectiveness. Take a multivitamin supplement at bedtime to ensure adequate fat-soluble vitamin intake. Most patients see the best results when treatment is continued for at least 12 weeks alongside consistent dietary changes.


