Is Orlistat Available Over The Counter? UK Weight Loss

pricing for mounjaro and wegovy weight loss

Orlistat 120mg requires a prescription in the UK but is available through our online clinical assessment. Following prescriber approval, generic orlistat costs from £29.69 for 4 weeks (with EDM10), whilst Xenical costs £38.69. Alli 60mg is the lower-strength option at £26.09. All three may help support weight management alongside a reduced-calorie, lower-fat diet. Our GPhC-registered pharmacy provides next day delivery across the UK with 10% off every order using code EDM10. Complete your online consultation today for fast, discreet access to prescription weight loss treatment.

  • Prescription orlistat from £15.20 per fortnight with clinical assessment included
  • Choice of generic orlistat, branded Xenical, or lower-strength Alli options
  • 10% discount on every order with code EDM10 for new and returning customers
  • Next day delivery from our GPhC-registered Leicester pharmacy nationwide
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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How to Access Prescription Orlistat in the UK

Reviewed by Mostafa Damghani · 03/07/2026

Orlistat Prescription Requirements in the UK

Orlistat 120mg is prescription-only in the UK and requires clinical assessment by a qualified healthcare professional. Unlike over-the-counter options, prescription-strength orlistat may help block approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet. Our online consultation replaces the need for a GP appointment, with UK-licensed prescribers reviewing your suitability for treatment within hours.

Available Orlistat Options and Pricing

We stock three orlistat formulations to suit different preferences and budgets. Generic orlistat 120mg offers the most cost-effective option at £29.69 for 84 capsules (4-week supply) with EDM10. Branded Xenical 120mg contains the identical active ingredient at £38.69 for the same quantity. For those preferring a lower-strength starting point, Alli 60mg costs £26.09 for 42 capsules. All prices include the prescription and clinical assessment, with 10% off using code EDM10.

How Prescription Orlistat Works

Orlistat works locally in your digestive system by inhibiting lipase enzymes responsible for breaking down dietary fat. This mechanism may help reduce the absorption of approximately one third of fat from your meals, which then passes naturally through your body. Unlike appetite suppressants that act on the brain, orlistat's effects are directly related to your dietary fat intake, making it essential to follow a lower-fat eating plan for optimal results and to minimise gastrointestinal side effects.

Online Prescription Process

Access prescription orlistat through our streamlined online service. Complete a comprehensive health questionnaire covering your medical history, current medications, and weight management goals. A UK-licensed prescriber reviews your information and, where clinically appropriate, issues a prescription. Your medication is then dispensed by our GPhC-registered pharmacy in Leicester and dispatched for next day delivery in discreet packaging.

Comparing Your Orlistat Options

Generic orlistat 120mg and branded Xenical 120mg contain identical active ingredients and offer equivalent clinical effects. The primary difference is cost, with generic orlistat saving approximately £9 per month compared to Xenical. Both require the same prescription process and dosing schedule of one capsule three times daily with main meals containing fat. Alli 60mg provides half the dose for those preferring a gentler introduction to orlistat therapy, though clinical effects may be correspondingly reduced.

Treatment Suitability and Safety

Orlistat may be suitable for adults with a BMI of 30 or above, or 28 or above with weight-related health conditions such as type 2 diabetes or high blood pressure. The prescriber assessment considers your individual circumstances, medical history, and current medications. Like all prescription medicines, orlistat may cause side effects, typically gastrointestinal effects that can be minimised by keeping meals low in fat content.

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Is orlistat 120mg available over the counter in the UK?
No, orlistat 120mg requires a prescription in the UK. However, you can access it through our online clinical assessment without visiting a GP. Complete your consultation today for fast prescriber review.
How much does prescription orlistat cost compared to Xenical?
Generic orlistat 120mg costs £29.69 for 4 weeks with EDM10, whilst branded Xenical costs £38.69 for the same supply. Both include the prescription and clinical assessment in the price.
How quickly can I receive orlistat after ordering?
Following prescriber approval of your online consultation, we dispatch your orlistat for next day delivery from our GPhC-registered pharmacy. Most consultations are reviewed within hours during working days.
Is buying orlistat online from EverydayMeds safe and legal?
Yes, we're a GPhC-registered pharmacy based in Leicester with MHRA-regulated supply chains. All prescriptions are issued by UK-licensed healthcare professionals following clinical assessment, meeting the same standards as traditional pharmacies.
What's the difference between orlistat, Xenical, and Alli?
Orlistat 120mg and Xenical 120mg contain identical active ingredients at the same dose - Xenical is simply the branded version. Alli contains 60mg orlistat, half the prescription strength. All support weight management alongside a lower-fat diet.