Compare Orlistat vs Xenical Prices and Choose
Orlistat vs Xenical: The Key Differences
Orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical strength. The clinical effect is equivalent - both block approximately one third of dietary fat absorption when taken with meals. The main difference is cost. Generic orlistat offers the same weight management support at a lower price, while Xenical is the original branded version manufactured by Roche.
Price Comparison: Significant Savings with Generic
At EverydayMeds, the price difference is substantial. Generic orlistat 120mg costs £29.69 for 4 weeks with code EDM10, compared to £38.69 for branded Xenical - saving you over £100 annually. For 12-week supplies, orlistat costs £86.39 versus Xenical at £116.09, representing £30 savings per 3-month period. Both require prescription following clinical assessment.
Consider Alli 60mg as Lower-Strength Alternative
Alli 60mg offers half the strength of prescription orlistat, providing a gentler introduction to fat-blocking treatment. At £26.09 for 4 weeks with EDM10, Alli may suit those preferring lower-dose treatment or experiencing side effects with 120mg strength. However, the lower dose means proportionally less dietary fat blocking compared to prescription-strength options.
How Both Products Work Identically
Whether you choose orlistat or Xenical, both work by inhibiting lipase enzymes in your digestive system. This prevents approximately one third of dietary fat from being absorbed, with unabsorbed fat passing naturally through the body. Both must be taken with each main meal containing fat, alongside a reduced-calorie, lower-fat diet for optimal results.
Which Should You Choose?
Choose generic orlistat 120mg if cost is your priority - you'll receive identical clinical benefits at lower cost. Choose Xenical 120mg if you prefer branded medication from the original manufacturer. Both require the same online clinical assessment process and are dispensed by our GPhC-registered pharmacy in Leicester with next day delivery across the UK.
Order Your Prescription Today
Complete your online clinical assessment for orlistat or Xenical today. Our UK-licensed prescribers will review your information and, if appropriate, issue your prescription. Use code EDM10 for 10% off every order. All orders include prescription, dispensing, and tracked delivery - no separate GP appointment required.


