Which Should You Choose: Generic Orlistat or Xenical?
Orlistat vs Xenical: The Key Facts
Both orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. They work by the same mechanism - inhibiting lipase enzymes in your gut to block approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body. Clinically, there is no difference in effectiveness between generic orlistat and branded Xenical.
Price Comparison: How Much You Can Save
Generic orlistat offers substantial savings versus branded Xenical. For a 4-week supply (84 capsules), generic orlistat costs £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10). Over 12 weeks, you'll save approximately £27 by choosing generic orlistat at £95.99 (£86.39 with EDM10) versus Xenical at £128.99 (£116.09 with EDM10).
Correct Dosing: Three Times Daily Maximum
Both orlistat and Xenical should be taken three times daily - never four times. Take one 120mg capsule with each main meal containing fat, or up to one hour after eating. If you skip a meal or eat a fat-free meal, you can skip that dose. This provides 21 capsules per week, making our 42-capsule packs a 2-week supply and 84-capsule packs a 4-week supply.
Consider Alli 60mg as an Alternative
Alli 60mg offers half the strength of prescription orlistat, also taken three times daily with meals. At £28.99 for 4 weeks (£26.09 with EDM10), Alli provides a lower-dose option for those preferring to start with a gentler strength. However, clinical studies show 120mg orlistat is more effective for weight management.
Our Recommendation: Choose by Budget
If cost is your priority, generic orlistat 120mg delivers identical clinical benefits at the lowest price. If you prefer branded medication from the original manufacturer Roche, Xenical remains excellent value with our EDM10 discount. Both require the same online clinical assessment by our UK-licensed prescribers and are dispensed from our GPhC-registered pharmacy in Leicester.
How to Order Today
Complete our online health questionnaire for clinical assessment. Our UK-licensed prescribers will review your information and issue a prescription if clinically appropriate. Orders are dispatched next day in discreet packaging. Use code EDM10 for 10% off your order - available for new and returning customers on all orlistat, Xenical and Alli purchases.


