Comparing Your Prescription Weight Loss Options
Orlistat vs Xenical: The Clinical Facts
Both orlistat 120mg and Xenical 120mg are clinically equivalent prescription weight loss medications. They contain the same active ingredient at the same dose and work by blocking approximately one third of dietary fat absorption. The key difference lies in cost and manufacturer - generic orlistat is produced by various manufacturers, whilst Xenical is the branded version made by Roche.
Cost Comparison: Significant Savings Available
Generic orlistat offers substantial savings over Xenical without compromising clinical effectiveness. A 4-week supply of orlistat costs £32.99 (£29.69 with EDM10), compared to Xenical at £42.99 (£38.69 with EDM10). Over 12 weeks, orlistat costs £95.99 (£86.39 with EDM10) versus Xenical at £128.99 (£116.09 with EDM10) - a saving of £33 per 12-week course.
How Both Medications Work
Whether you choose orlistat or Xenical, the mechanism is identical. Both inhibit lipase enzymes in the gut, preventing approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through the digestive system. Both medications must be used alongside a reduced-calorie, lower-fat diet and increased physical activity to support effective weight management.
What About Alli 60mg?
Alli contains half the dose at 60mg orlistat and is available without prescription. However, the lower dose means it blocks a smaller proportion of dietary fat compared to prescription-strength options. Alli 12-week supply costs £129.99 (£116.99 with EDM10). Many patients prefer the enhanced effect of prescription-strength orlistat 120mg or Xenical 120mg following clinical assessment.
Which Should You Choose?
The decision between orlistat and Xenical often comes down to personal preference and budget. Both require prescription following individual clinical assessment by a UK-licensed prescriber. Some patients prefer branded Xenical, whilst others choose generic orlistat for the cost savings. Your prescriber can discuss which option may be most suitable during your online consultation.
Starting Your Treatment
Complete our online clinical assessment today to determine your suitability for prescription weight loss treatment. Our UK-licensed prescribers will review your information and, if appropriate, issue a prescription for either orlistat or Xenical based on your preference. Treatment is dispensed by our GPhC-registered pharmacy in Leicester with next day delivery available. Use code EDM10 for 10% off your order.


