Orlistat vs Xenical vs Alli UK: Compare & Buy Online

pricing for mounjaro and wegovy weight loss

Choosing between Orlistat, Xenical, and Alli for weight loss? All contain the same active ingredient but differ in strength and price. Generic Orlistat 120mg offers the best value from £29.69 for 4 weeks, whilst branded Xenical 120mg costs £38.69. Alli 60mg provides a lower-strength option at £26.09. All require clinical assessment by UK-licensed prescribers and work by blocking approximately one third of dietary fat absorption alongside a reduced-calorie, lower-fat diet. Compare prices and order online with 10% off using code EDM10.

  • Same clinical effect - Orlistat and Xenical contain identical active ingredients
  • Save £9+ monthly choosing generic Orlistat over branded Xenical
  • Lower-strength Alli 60mg available for gradual weight management approach
  • Next day delivery from GPhC-registered pharmacy with prescription included
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Which Orlistat Product Should You Choose?

Reviewed by Mostafa Damghani · 03/07/2026

Orlistat 120mg vs Xenical 120mg: The Key Difference

Both Orlistat 120mg and Xenical 120mg contain identical active ingredients at the same dose. The primary difference is cost - generic Orlistat offers significant savings whilst delivering the same clinical effect. A 4-week supply of Orlistat costs £29.69 with EDM10, compared to £38.69 for Xenical - saving you over £100 annually. Both work by blocking approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet.

Complete Price Comparison

Orlistat 120mg pricing: 2 weeks (42 capsules) £15.20, 4 weeks (84 capsules) £29.69, 8 weeks (168 capsules) £57.59, 12 weeks (252 capsules) £86.39. Xenical 120mg pricing: 2 weeks £19.35, 4 weeks £38.69, 8 weeks £78.29, 12 weeks £116.09. All prices include 10% discount with code EDM10. Both require prescription following online clinical assessment by UK-licensed prescribers.

Alli 60mg: Lower-Strength Alternative

Alli contains half the dose of prescription-strength orlistat, making it suitable for those preferring a gradual approach. At £26.09 for 4 weeks with EDM10, Alli blocks a smaller proportion of dietary fat with typically milder gastrointestinal effects. However, the lower dose means reduced clinical potency compared to 120mg formulations.

How All Three Products Work

Whether you choose Orlistat, Xenical, or Alli, the mechanism remains the same - inhibiting lipase enzymes in your digestive system to prevent approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body. All work best when meals contain no more than 15g fat each, significantly reducing the likelihood of gastrointestinal side effects whilst maximising weight management support.

Making Your Decision

For identical clinical effect at the lowest cost, choose generic Orlistat 120mg. If you prefer branded medication, Xenical 120mg provides the same active ingredient from the original manufacturer. For a lower-strength starting point, Alli 60mg offers a gentler introduction to orlistat therapy. All options require commitment to a reduced-calorie, lower-fat diet and regular physical activity for optimal results.

Order Online Today

Complete your online clinical assessment to determine suitability. Following prescriber approval, your chosen orlistat product will be dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly to your address. Use code EDM10 for 10% off every order, with next day delivery available across the UK.

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What's the difference between Alli, Orlistat and Xenical for weight loss?
Orlistat 120mg and Xenical 120mg contain identical active ingredients - the main difference is price, with generic Orlistat costing significantly less. Alli contains 60mg (half dose) for a gentler approach. All require clinical assessment and work alongside a reduced-calorie, lower-fat diet.
How much can I save choosing Orlistat over Xenical?
You'll save £9 per month choosing generic Orlistat at £29.69 for 4 weeks versus Xenical at £38.69 (with EDM10). Over 12 weeks, generic Orlistat costs £86.39 compared to Xenical at £116.09 - saving £29.70.
How do I order orlistat online in the UK?
Complete our online health questionnaire for review by a UK-licensed prescriber. Following clinical approval, your prescription will be dispensed by our GPhC-registered pharmacy and delivered next day. Use code EDM10 for 10% off every order.
Is buying orlistat online from EverydayMeds legitimate?
Yes, we're a fully GPhC-registered online pharmacy based in Leicester, operating under MHRA regulations. All prescriptions are reviewed by qualified UK-licensed healthcare professionals using the same legal standards as traditional pharmacies.
How quickly can I receive my orlistat prescription?
Following prescriber approval of your online assessment, orders are typically dispatched the same day with next day delivery available across the UK. All medication is packaged discreetly and includes tracked delivery.