Orlistat vs Xenical UK: Which Weight Loss Tablet to Buy, Explained

pricing for mounjaro and wegovy weight loss

Choosing between Orlistat 120mg and Xenical 120mg? Both contain identical active ingredients and work the same way, but there's a key difference: price. Generic Orlistat costs from £15.20 for 2 weeks (with code EDM10), whilst branded Xenical costs from £19.35. Both require a prescription following clinical assessment by our UK-licensed prescribers. Save money with generic Orlistat or choose branded Xenical – the clinical effect is identical. Complete your online consultation today and get next day delivery from our GPhC-registered Leicester pharmacy.

  • Same active ingredient – Orlistat 120mg in both products
  • Save up to £30 per 12-week course choosing generic over branded
  • Fast online prescription service with UK-licensed prescribers
  • 10% off every order with code EDM10 – new and returning customers
Start your free consultation

Takes less than 2 minutes to complete, 100% online

usp of our everydaymeds for mounjaro and wegovy
pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

Live Pricing

Our Pricing

offeroral.svg__PID:96a5c4aa-5435-4906-b3cf-f5a48b157d30

Compare Prices: Orlistat vs Xenical vs Alli

Reviewed by Mostafa Damghani · 03/07/2026

Orlistat vs Xenical: The Key Differences

When researching weight loss tablets, you'll encounter Orlistat 120mg and Xenical 120mg. Here's what you need to know: they contain exactly the same active ingredient at identical doses. Xenical is the branded version manufactured by Roche, whilst Orlistat is the generic equivalent. Both work by blocking approximately one third of dietary fat absorption and require a prescription following clinical assessment.

Price Comparison: Significant Savings Available

The main difference is cost. Generic Orlistat 84 capsules (4-week supply) costs £32.99, reduced to £29.69 with code EDM10. Branded Xenical 84 capsules costs £42.99, reduced to £38.69 with EDM10. Over a 12-week course, choosing generic Orlistat saves approximately £30 compared to Xenical. For a 12-week supply, Orlistat costs £95.99 (£86.39 with EDM10) versus Xenical at £128.99 (£116.09 with EDM10).

Clinical Effectiveness: Identical Results

Both Orlistat and Xenical are clinically equivalent. They contain 120mg orlistat, taken three times daily with meals containing fat. Both may help reduce dietary fat absorption when used alongside a reduced-calorie, lower-fat diet and increased physical activity. Your choice comes down to personal preference and budget – some patients prefer branded medications, whilst others choose generic options for better value.

Alli 60mg: The Lower-Strength Alternative

Alli contains 60mg orlistat – half the prescription dose. Available in 42-capsule packs (4-week supply) for £28.99 (£26.09 with EDM10), Alli provides a lower-strength option for those preferring to start with a milder dose. However, the prescription-strength options (Orlistat 120mg or Xenical 120mg) are clinically more potent for weight management support.

Side Effects: Same Profile for Both

As both products contain identical active ingredients, the side effect profile is the same. Most side effects are gastrointestinal and directly related to dietary fat intake. Common effects include oily stools, increased bowel movement frequency, and abdominal discomfort. These can be minimised by keeping meals low in fat (approximately 15g per meal). Like all prescription medicines, both may cause side effects, and you should seek medical advice if effects are severe or persistent.

Online Prescription Process

Both Orlistat and Xenical require prescription following online clinical assessment. Complete our health questionnaire, including medical history and BMI information. A UK-licensed prescriber reviews your information and issues a prescription where clinically appropriate. Treatment is dispensed by our GPhC-registered pharmacy in Leicester with next day delivery available. The prescription is included in the price – no separate GP appointment needed.

Which Should You Choose?

For identical clinical effects at lower cost, choose generic Orlistat 120mg. If you prefer branded medications, Xenical 120mg delivers the same results. Both are suitable for adults with BMI 30+ or BMI 28+ with weight-related health conditions, subject to prescriber approval. Start your clinical assessment today and save 10% with code EDM10 on every order.

Looking to start your weight loss journey?
Take a quick eligibility quiz to explore your options and see how we can support you.
Start your consultation

How it
Works?

Group 469326.png__PID:d1d71928-56cc-4f79-bdc7-0a45d0bc6b99
Background (1).png__PID:62282697-4455-4e74-a869-705c14f98b30
Background (3).png__PID:72aeaaf6-bb5b-4dd5-8914-6efdf80a1555

Start your
assessment for
Oral Weight Loss

Start your journey to better health today.

List.svg__PID:b4a5b990-cf62-48e4-ba8f-0a8bffce6cc6

Start your journey to better health today.

Once you complete a short online assessment, you’ll be able to choose your preferred treatment and quantity from a list of safe, medically approved options tailored to you.

Start My Assessment

Returning customer?

Log in to Your Account

FAQs

Frequently asked questions

Still have questions?

Our UK pharmacists are happy to help. There is no charge and no obligation.

  • Mon–Fri, 9am–5pm
What's the difference between www.alli.com products and UK Orlistat/Xenical?
Alli 60mg is lower-strength orlistat, whilst prescription Orlistat and Xenical contain 120mg. All work the same way but prescription strength is more potent. Complete our clinical assessment to determine the most suitable option for your weight management goals.
How much can I save choosing Orlistat over Xenical?
Generic Orlistat saves approximately £9 per 4-week supply compared to branded Xenical. Over 12 weeks, you'll save around £30. With code EDM10, Orlistat 84 capsules costs £29.69 versus Xenical at £38.69 – identical clinical effect for less money.
How do I get a prescription for Orlistat or Xenical online?
Complete our online health questionnaire including medical history and BMI details. A UK-licensed prescriber reviews your information and issues a prescription where appropriate. Treatment is then dispensed and dispatched with next day delivery available.
Are online prescriptions for Orlistat legitimate and safe?
Yes, we're a GPhC-registered pharmacy based in Leicester with MHRA-regulated supply chains. Our UK-licensed prescribers follow the same clinical standards as NHS services. All treatments are genuine, sourced through licensed pharmaceutical suppliers.
How quickly can I receive my Orlistat or Xenical order?
Following prescriber approval, orders are dispatched the same day with next day delivery available. All packaging is discreet and tracked. Use code EDM10 for 10% off your order with fast, secure delivery across the UK.