Which Should You Choose: Orlistat or Xenical?
How Orlistat and Xenical Help with Weight Loss
Both orlistat 120mg and Xenical 120mg work by blocking approximately one third of the fat you eat from being absorbed. They inhibit lipase enzymes in your digestive system, allowing unabsorbed fat to pass naturally through your body. This can help reduce calorie intake from dietary fat when used alongside a reduced-calorie, lower-fat diet and increased physical activity.
Generic Orlistat vs Branded Xenical: The Key Differences
Orlistat 120mg and Xenical 120mg are clinically equivalent - they contain the same active ingredient at the same dose. The main difference is cost. Our generic orlistat 4-week supply costs £32.99 (£29.69 with EDM10), whilst Xenical costs £42.99 (£38.69 with EDM10). This means choosing generic orlistat can save you approximately £9 monthly. Both medications are manufactured to the same MHRA standards and dispensed by our GPhC-registered pharmacy.
Pricing Comparison: Making Your Decision
Generic orlistat pricing: 2 weeks £16.89 (£15.20 with EDM10), 4 weeks £32.99 (£29.69 with EDM10), 8 weeks £63.99 (£57.59 with EDM10), 12 weeks £95.99 (£86.39 with EDM10). Xenical pricing: 2 weeks £21.50 (£19.35 with EDM10), 4 weeks £42.99 (£38.69 with EDM10), 8 weeks £86.99 (£78.29 with EDM10), 12 weeks £128.99 (£116.09 with EDM10). Both options require the same dosing - one capsule three times daily with main meals containing fat.
Alli 60mg: The Lower-Strength Alternative
Alli 60mg contains half the dose of prescription-strength orlistat. It may be suitable for those preferring a lower-strength starting point, though it blocks a smaller proportion of dietary fat. Alli pricing: 4 weeks £28.99 (£26.09 with EDM10), 8 weeks £54.99 (£49.49 with EDM10), 12 weeks £129.99 (£116.99 with EDM10). Like prescription-strength options, Alli works best alongside a reduced-calorie, lower-fat diet.
Online Prescription Process
Both orlistat 120mg and Xenical 120mg require prescription following clinical assessment. Our UK-licensed prescribers review your online health questionnaire to determine suitability. Treatment may be appropriate for adults with BMI 30+ or BMI 28+ with weight-related health conditions. Following prescriber approval, your medication is dispensed by our Leicester-based GPhC-registered pharmacy and delivered discreetly with next-day delivery available. The prescription is included in the price - no separate GP appointment needed.


