Which Orlistat Product Should You Choose?
Orlistat 120mg vs Xenical 120mg: The Key Facts
Both Orlistat 120mg and Xenical 120mg contain the same active ingredient at identical doses, making them clinically equivalent. The primary difference lies in cost and branding. Generic orlistat is manufactured by various licensed pharmaceutical companies, while Xenical is the branded version produced by Roche.
Price Comparison: Orlistat vs Xenical
Generic orlistat offers significant savings compared to branded Xenical. For a 4-week supply (84 capsules), orlistat costs £32.99 (£29.69 with EDM10) versus Xenical at £42.99 (£38.69 with EDM10). Over 12 weeks, you could save approximately £30 by choosing generic orlistat at £95.99 (£86.39 with EDM10) compared to Xenical at £128.99 (£116.09 with EDM10).
Do Both Products Need a Prescription?
Yes, both Orlistat 120mg and Xenical 120mg are prescription-only medicines in the UK. Following an online clinical assessment by a UK-licensed prescriber, either product can be prescribed where clinically appropriate. The prescriber will assess your BMI, medical history, and weight-related health factors to determine suitability.
How Do They Work?
Both products work identically by inhibiting lipase enzymes in the gut, blocking approximately one third of dietary fat absorption. The unabsorbed fat passes naturally through the digestive system. This mechanism supports weight management when used alongside a reduced-calorie, lower-fat diet and increased physical activity.
Alli 60mg: The Lower-Strength Alternative
For those preferring a lower-strength option, Alli 60mg contains half the dose of prescription-strength orlistat. Available in 4-week supplies at £28.99 (£26.09 with EDM10), Alli provides a gentler introduction to orlistat therapy with typically milder side effects.
Making Your Choice
If you're looking for the most cost-effective option, generic Orlistat 120mg provides identical clinical benefits at a lower price. Some patients prefer the branded Xenical for personal preference reasons. Both options are dispensed by our GPhC-registered pharmacy in Leicester with next day delivery available across the UK.
Start Your Clinical Assessment Today
Complete our online health questionnaire to begin your clinical assessment. Our UK-licensed prescribers will review your information and, where appropriate, prescribe either orlistat or Xenical based on your preferences and clinical needs. Use code EDM10 for 10% off every order.


