Orlistat vs Xenical: Does Orlistat Need a Prescription?

pricing for mounjaro and wegovy weight loss

Both Orlistat 120mg and Xenical 120mg require a prescription and contain identical active ingredients at the same dose. The key difference is price — generic Orlistat costs £29.69 for 4 weeks compared to Xenical at £38.69 (with EDM10 discount). Both work by blocking approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet. Following an online clinical assessment by a UK-licensed prescriber, you can access both options through our GPhC-registered pharmacy. Get 10% off every order with code EDM10.

  • Same active ingredient — orlistat 120mg in both products
  • Generic orlistat saves approximately £9 per month vs Xenical
  • Both require prescription following clinical assessment
  • Next day delivery from GPhC-registered Leicester pharmacy
Start your free consultation

Takes less than 2 minutes to complete, 100% online

usp of our everydaymeds for mounjaro and wegovy
pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

Live Pricing

Our Pricing

offeroral.svg__PID:96a5c4aa-5435-4906-b3cf-f5a48b157d30

Which Orlistat Product Should You Choose?

Orlistat 120mg vs Xenical 120mg: The Key Facts

Both Orlistat 120mg and Xenical 120mg contain the same active ingredient at identical doses, making them clinically equivalent. The primary difference lies in cost and branding. Generic orlistat is manufactured by various licensed pharmaceutical companies, while Xenical is the branded version produced by Roche.

Price Comparison: Orlistat vs Xenical

Generic orlistat offers significant savings compared to branded Xenical. For a 4-week supply (84 capsules), orlistat costs £32.99 (£29.69 with EDM10) versus Xenical at £42.99 (£38.69 with EDM10). Over 12 weeks, you could save approximately £30 by choosing generic orlistat at £95.99 (£86.39 with EDM10) compared to Xenical at £128.99 (£116.09 with EDM10).

Do Both Products Need a Prescription?

Yes, both Orlistat 120mg and Xenical 120mg are prescription-only medicines in the UK. Following an online clinical assessment by a UK-licensed prescriber, either product can be prescribed where clinically appropriate. The prescriber will assess your BMI, medical history, and weight-related health factors to determine suitability.

How Do They Work?

Both products work identically by inhibiting lipase enzymes in the gut, blocking approximately one third of dietary fat absorption. The unabsorbed fat passes naturally through the digestive system. This mechanism supports weight management when used alongside a reduced-calorie, lower-fat diet and increased physical activity.

Alli 60mg: The Lower-Strength Alternative

For those preferring a lower-strength option, Alli 60mg contains half the dose of prescription-strength orlistat. Available in 4-week supplies at £28.99 (£26.09 with EDM10), Alli provides a gentler introduction to orlistat therapy with typically milder side effects.

Making Your Choice

If you're looking for the most cost-effective option, generic Orlistat 120mg provides identical clinical benefits at a lower price. Some patients prefer the branded Xenical for personal preference reasons. Both options are dispensed by our GPhC-registered pharmacy in Leicester with next day delivery available across the UK.

Start Your Clinical Assessment Today

Complete our online health questionnaire to begin your clinical assessment. Our UK-licensed prescribers will review your information and, where appropriate, prescribe either orlistat or Xenical based on your preferences and clinical needs. Use code EDM10 for 10% off every order.

How it
Works?

Group 469326.png__PID:d1d71928-56cc-4f79-bdc7-0a45d0bc6b99
Background (1).png__PID:62282697-4455-4e74-a869-705c14f98b30
Background (3).png__PID:72aeaaf6-bb5b-4dd5-8914-6efdf80a1555

Start your
assessment for
Oral Weight Loss

Start your journey to better health today.

List.svg__PID:b4a5b990-cf62-48e4-ba8f-0a8bffce6cc6

Start your journey to better health today.

Once you complete a short online assessment, you’ll be able to choose your preferred treatment and quantity from a list of safe, medically approved options tailored to you.

Start My Assessment

Returning customer?

Log in to Your Account

Frequently asked questions