Orlistat vs Xenical UK: Which Should You Buy?

pricing for mounjaro and wegovy weight loss

Orlistat 120mg and Xenical 120mg contain the same active ingredient at identical doses - the key difference is price. Generic orlistat starts from £15.20 with EDM10 (10% off), whilst branded Xenical costs from £19.35 with the same discount. Both require clinical assessment and work by blocking approximately one third of dietary fat absorption. Whether you choose cost-effective generic orlistat or prefer branded Xenical, both support weight management alongside a reduced-calorie, lower-fat diet. Complete your online assessment today to see which option suits you best.

  • Same clinical effect - both contain orlistat 120mg
  • Generic orlistat saves £9+ per month vs Xenical
  • Next day delivery from GPhC-registered pharmacy
  • 10% off every order with code EDM10
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Which Should You Choose: Generic or Branded?

Reviewed by Mostafa Damghani · 03/07/2026

Orlistat vs Xenical: The Clinical Facts

Both orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. They work by inhibiting lipase enzymes in the gut to block approximately one third of dietary fat absorption. Clinically, there is no difference in effectiveness - both may help support weight management when used alongside a reduced-calorie, lower-fat diet and regular physical activity.

Price Comparison: Generic vs Branded

The most significant difference is cost. Generic orlistat 120mg costs £29.69 for a 4-week supply with EDM10, whilst Xenical 120mg costs £38.69 for the same period - saving you over £9 per month. For a 12-week course, orlistat costs £86.39 compared to Xenical at £116.09, representing substantial savings of nearly £30.

Who May Be Suitable for 120mg Strength

Both orlistat and Xenical require clinical assessment and are prescription-only medicines. Following online consultation with a UK-licensed prescriber, they may be suitable for adults with a BMI of 30 or above, or 28+ with weight-related health conditions such as type 2 diabetes or high blood pressure. Treatment suitability is assessed individually based on your health circumstances.

Consider Alli 60mg as an Alternative

For those preferring a lower-strength option, Alli 60mg contains half the dose of prescription orlistat. At £26.09 for a 4-week supply with EDM10, it offers a gentler introduction to orlistat treatment with typically milder side effects. However, it blocks a smaller proportion of dietary fat compared to the 120mg prescription strength.

Side Effects: Same for Both Products

Since both contain identical active ingredients, side effects are the same. Most are gastrointestinal and linked to dietary fat intake - including oily stools, urgent bowel movements, and flatulence. These can be minimised by keeping meals low in fat (approximately 15g per meal). Side effects often reduce as your diet adapts to lower fat intake.

How to Order Through EverydayMeds

Complete our online health questionnaire for clinical review by a UK-licensed prescriber. If suitable, your prescription will be dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly to your address with next day delivery available. Use code EDM10 for 10% off both orlistat and Xenical options.

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Can I take orlistat when not overweight for weight maintenance?
Orlistat requires clinical assessment and is typically prescribed for adults with BMI 28+ with health conditions or BMI 30+. Your prescriber will determine suitability based on individual circumstances. Complete our online consultation to discuss your options.
How much can I save choosing generic orlistat over Xenical?
Generic orlistat costs £29.69 for 4 weeks vs Xenical at £38.69 - saving over £9 monthly. For 12-week supplies, you save nearly £30 choosing orlistat at £86.39 vs Xenical at £116.09 (all prices with EDM10).
How quickly can I receive my orlistat prescription?
Following online assessment and prescriber approval, orders are dispensed by our GPhC-registered pharmacy with next day delivery available across the UK. Your prescription is included in the price with no separate GP visit needed.
Is buying orlistat online safe and legal?
Yes - EverydayMeds is a GPhC-registered online pharmacy based in Leicester with UK-licensed prescribers. All medication is sourced through licensed UK pharmaceutical supply chains and regulated by the MHRA for your safety.
What's included with my orlistat order?
Your order includes clinical assessment, prescription if appropriate, medication dispensed by qualified pharmacists, and discreet tracked delivery. Use code EDM10 for 10% off every order including both new and returning customers.