Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Clinical Facts
Orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. Both work by blocking approximately one third of dietary fat absorption in your digestive system. Clinically, there is no difference in effectiveness - they are bioequivalent medications. The choice comes down to personal preference and budget considerations.
Price Comparison: Significant Savings Available
Generic Orlistat offers substantial savings versus branded Xenical. For a 4-week supply (84 capsules), Orlistat costs £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10). Over 12 weeks, you could save £33 by choosing generic Orlistat at £95.99 (£86.39 with EDM10) versus Xenical at £128.99 (£116.09 with EDM10). Both medications deliver identical clinical results.
Alli 60mg: Lower-Strength Alternative
Alli contains half the orlistat dose at 60mg per capsule. This lower-strength option blocks a smaller proportion of dietary fat and typically causes milder side effects. Alli 4-week supply costs £28.99 (£26.09 with EDM10). Some patients prefer starting with Alli before progressing to 120mg strength if needed.
How Both Medications Work
Orlistat and Xenical work identically by inhibiting lipase enzymes in your gut. This prevents approximately one third of dietary fat from being absorbed into your body. The unabsorbed fat passes naturally through your digestive system. Both must be taken alongside a reduced-calorie, lower-fat diet for optimal results. Take one capsule three times daily with each main meal containing fat.
Side Effects: Identical Profiles
Both medications may cause similar gastrointestinal side effects including oily stools, increased bowel frequency, and urgent toilet visits. These effects are directly related to dietary fat intake - keeping meals low in fat (approximately 15g per meal) significantly reduces side effects. Most patients find side effects diminish as they adapt their diet.
Getting Your Prescription Online
Both Orlistat and Xenical require prescription following clinical assessment. Our UK-licensed prescribers review your online health questionnaire to determine suitability. Eligible patients typically have BMI 30+ or BMI 28+ with weight-related health conditions. Complete your assessment today and receive next day delivery from our GPhC-registered pharmacy with 10% off using code EDM10.
