What's the Difference Between Orlistat and Xenical?

pricing for mounjaro and wegovy weight loss

Orlistat and Xenical both contain identical 120mg orlistat - the key difference is cost. Generic orlistat offers the same clinical effect as branded Xenical at a significantly lower price. Both are prescription-only weight loss treatments that may help support weight management alongside a reduced-calorie, lower-fat diet. At EverydayMeds, generic orlistat costs from £29.69 for 4 weeks (with EDM10 discount) compared to £38.69 for Xenical. Both require clinical assessment by a UK-licensed prescriber and are dispensed by our GPhC-registered pharmacy with next-day delivery. Start your weight management journey today with 10% off using code EDM10.

  • Same active ingredient - both contain 120mg orlistat for identical clinical effects
  • Significant cost savings - generic orlistat saves approximately £9 per month vs Xenical
  • Prescription included - no separate GP appointment needed, assessed by UK-licensed prescribers
  • Next-day delivery from GPhC-registered Leicester pharmacy with 10% off every order
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Understanding Your Prescription Weight Loss Options

Orlistat vs Xenical: The Clinical Facts

Both orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. They work by blocking approximately one third of dietary fat absorption in your gut, supporting weight management when used alongside a reduced-calorie, lower-fat diet and increased physical activity. The clinical effect is identical - the primary difference lies in cost and manufacturer.

Cost Comparison: Generic vs Branded

Generic orlistat represents exceptional value compared to branded Xenical. A 4-week supply of orlistat costs £32.99 (£29.69 with EDM10), while Xenical costs £42.99 (£38.69 with EDM10) - saving you approximately £9 per month. For a 12-week course, orlistat costs £95.99 (£86.39 with EDM10) compared to Xenical at £128.99 (£116.09 with EDM10), representing savings of over £30.

How Both Products Work

Whether you choose orlistat or Xenical, the mechanism is identical. Both inhibit lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body, potentially reducing calorie intake from fat as part of your weight management programme. Both must be taken three times daily with main meals containing fat.

Who Can Access Prescription Weight Loss Treatment

Both orlistat and Xenical are prescription-only medicines suitable for adults with a BMI of 30 or above, or 28 and above with weight-related health conditions such as type 2 diabetes or high blood pressure. Following an online clinical assessment, a UK-licensed prescriber will determine if treatment is appropriate for your circumstances. Our streamlined process eliminates the need for separate GP appointments.

Alli 60mg: The Lower-Dose Alternative

Alli contains half the dose of prescription-strength orlistat at 60mg. While clinically less potent, it may suit those preferring a lower-strength starting point. Alli costs £28.99 for 4 weeks (£26.09 with EDM10). All three options require commitment to dietary changes for optimal results.

Order Today with Confidence

Choose from orlistat, Xenical, or Alli with complete confidence. All treatments are dispensed by our GPhC-registered pharmacy in Leicester, following MHRA regulations. Next-day delivery is available across the UK with discreet, secure packaging. Use code EDM10 for 10% off every order, whether you're a new or returning customer.

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Once you complete a short online assessment, you’ll be able to choose your preferred treatment and quantity from a list of safe, medically approved options tailored to you.

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