Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Facts
When comparing orlistat 120mg and Xenical 120mg, you're looking at two clinically equivalent treatments. Both contain exactly the same active ingredient - orlistat 120mg - and work identically by inhibiting lipase enzymes to block approximately one third of dietary fat absorption. The primary difference lies in cost, with generic orlistat offering substantial savings over branded Xenical.
Price Comparison: Significant Savings with Generic Orlistat
Generic orlistat 120mg costs £32.99 for a 4-week supply (84 capsules), reduced to £29.69 with code EDM10. Branded Xenical costs £42.99 for the same supply, or £38.69 with EDM10 - a difference of £9 per month. Over a 12-week treatment period, you could save £30 by choosing generic orlistat (£86.39 vs £116.09 with EDM10).
Clinical Effectiveness: Identical Results
Both orlistat and Xenical deliver the same clinical effect when used alongside a reduced-calorie, lower-fat diet. Each works by blocking approximately one third of dietary fat from being absorbed, with the unabsorbed fat passing naturally through the digestive system. Treatment suitability requires assessment by a UK-licensed prescriber, typically for adults with a BMI of 30 or above, or 28 or above with weight-related health conditions.
Dosing and Administration
Both products follow identical dosing: one 120mg capsule taken three times daily with each main meal containing fat. Each capsule should be taken immediately before, during, or up to one hour after eating. If a meal contains no fat or is skipped, that dose can be omitted. Our pack sizes accommodate different treatment lengths: 42 capsules (2 weeks), 84 capsules (4 weeks), 168 capsules (8 weeks), and 252 capsules (12 weeks).
Consider Alli 60mg as an Alternative
Alli 60mg offers half the strength of prescription orlistat, containing 60mg of the same active ingredient. Whilst clinically less potent than 120mg formulations, Alli may suit those preferring a lower-strength starting option. A 4-week supply (42 capsules) costs £26.09 with EDM10.
Order Through Our Online Prescription Service
Both orlistat and Xenical require a prescription, which our UK-licensed prescribers can issue following an online clinical assessment. Complete our medical questionnaire, receive prescriber review, and benefit from next day delivery from our GPhC-registered pharmacy in Leicester. Use code EDM10 for 10% off every order - applicable to new and returning customers.


