Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Facts
Orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. Both work by blocking approximately one third of dietary fat absorption in your gut, helping support weight management alongside a reduced-calorie, lower-fat diet. The primary difference is manufacturer and price - Orlistat is the generic version whilst Xenical is the branded product made by Roche.
Cost Comparison: Significant Savings Available
Generic Orlistat offers substantial savings compared to branded Xenical. For a 4-week supply (84 capsules), Orlistat costs £29.69 with code EDM10, whilst Xenical costs £38.69 - saving you £9 per month. Over a 12-week programme, you could save over £29 by choosing generic Orlistat (£86.39) instead of Xenical (£116.09). Both options require the same online clinical assessment by UK-licensed prescribers.
Alli 60mg: The Lower-Strength Alternative
Alli offers half the dose of prescription-strength orlistat, making it suitable for those preferring a gentler approach. At 60mg, Alli typically produces milder gastrointestinal side effects whilst still helping block dietary fat absorption. A 4-week supply costs £26.09 with EDM10, positioning it between generic Orlistat and Xenical in terms of pricing.
Clinical Effectiveness: No Difference
Whether you choose Orlistat 120mg or Xenical 120mg, you receive identical clinical benefits. Both may help reduce the amount of dietary fat absorbed when used alongside appropriate dietary changes. The unabsorbed fat passes naturally through your digestive system. Your choice should be based on budget preferences rather than clinical considerations.
Which Patients Choose Which Option?
Cost-conscious patients typically prefer generic Orlistat for its proven value. Those who prefer branded medications often choose Xenical. First-time users sometimes select Alli 60mg to assess their response before progressing to 120mg strength. All three options are dispensed by our GPhC-registered pharmacy following prescriber approval.
Order Your Preferred Option Today
Complete our online clinical assessment to determine your suitability for orlistat treatment. UK-licensed prescribers will review your medical history and BMI to ensure safe, appropriate prescribing. Choose from 2, 4, 8, or 12-week supplies with next day tracked delivery across the UK. Use code EDM10 for 10% off your order.


