Generic vs Branded: Which Should You Choose?
Neither Xenical Nor Orlistat Cause Weight Gain
A common concern is whether Xenical can cause weight gain, but this is not how orlistat works. Both Xenical 120mg and generic orlistat 120mg contain the identical active ingredient at the same dose. They work by blocking approximately one third of dietary fat absorption in your gut - they cannot cause weight gain when used correctly alongside a reduced-calorie, lower-fat diet.
Orlistat vs Xenical: Key Differences
The only significant difference between generic orlistat and branded Xenical is cost. Generic orlistat 120mg offers identical clinical effects at a lower price point. For a 4-week supply, generic orlistat costs £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10) - saving you over £100 annually.
Clinical Equivalence Confirmed
Both products contain 120mg orlistat and work through the same mechanism - inhibiting lipase enzymes to prevent approximately one third of dietary fat absorption. The unabsorbed fat passes naturally through your system. Generic manufacturers must demonstrate bioequivalence to the original branded product, ensuring identical therapeutic effects.
Your Treatment Options
Orlistat 120mg capsules are available in multiple pack sizes: 42 capsules (2-week supply) from £15.20, 84 capsules (4-week supply) from £29.69, 168 capsules (8-week supply) from £57.59, and 252 capsules (12-week supply) from £86.39 with EDM10 discount. Xenical pricing starts from £19.35 for 42 capsules with the same discount code.
Consider Alli 60mg Alternative
For those preferring a lower-strength option, Alli 60mg contains half the orlistat dose of prescription-strength products. Available without prescription, Alli may be suitable for some adults, though it blocks a smaller proportion of dietary fat compared to 120mg products.
Online Prescription Process
Both orlistat 120mg and Xenical 120mg require prescription following clinical assessment. Complete our online health questionnaire for review by a UK-licensed prescriber. If approved, your treatment is dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly with next-day options available.
Making Your Decision
Choose generic orlistat 120mg for maximum value whilst receiving identical clinical benefits, or select branded Xenical if you prefer the original formulation. Both require the same commitment to a reduced-calorie, lower-fat diet for optimal results. Apply code EDM10 at checkout for 10% off your first and all subsequent orders.


