Which Should You Buy: Orlistat or Xenical?
Orlistat vs Xenical: The Clinical Facts
When comparing orlistat vs Xenical for weight loss success, the fundamental truth is simple: both contain exactly the same active ingredient at identical 120mg strength. Generic orlistat and branded Xenical work by blocking approximately one third of dietary fat absorption through lipase enzyme inhibition in your digestive system. The clinical effect is identical - your choice comes down to personal preference and budget considerations.
Price Comparison: Significant Savings Available
The most substantial difference between orlistat and Xenical is cost. At EverydayMeds, generic orlistat 120mg costs £32.99 for 84 capsules (4-week supply), reduced to £29.69 with discount code EDM10. Branded Xenical costs £42.99 for the same 84 capsules, reduced to £38.69 with EDM10. This represents savings of approximately £9 monthly when choosing generic orlistat. For longer-term treatment, these savings become more significant - 12-week supplies show savings of £29.70 when choosing orlistat (£86.39) over Xenical (£116.09) with EDM10 discount.
How Successful Is Weight Loss with Both Options?
Success with both orlistat and Xenical depends on the same factors: adherence to a reduced-calorie, lower-fat diet and regular physical activity. Both medications may support weight management by reducing absorption of approximately one third of dietary fat from meals. Individual responses vary significantly, but clinical studies show both forms of 120mg orlistat can contribute to weight reduction when used as part of a structured programme. The key to success lies in keeping meal fat content low (approximately 15g per meal) to maximise effectiveness and minimise gastrointestinal side effects.
Alli 60mg: The Lower-Strength Alternative
For those preferring a gentler approach, Alli 60mg offers half the dose of prescription-strength orlistat. At £26.09 for 4 weeks with EDM10, Alli blocks a smaller proportion of dietary fat but typically causes milder side effects. Some patients start with Alli before progressing to 120mg strength, while others prefer the lower dose long-term. All three options require commitment to dietary changes for optimal results.
Getting Your Prescription Through EverydayMeds
Both orlistat 120mg and Xenical 120mg require prescription following clinical assessment by a UK-licensed prescriber. Our streamlined online consultation process reviews your medical history, current medications, and weight management goals. If treatment is deemed appropriate, your prescription is dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly to your address with next day delivery available. The prescription is included in the price - no separate GP appointment needed.
Managing Side Effects Successfully
Both orlistat and Xenical may cause identical gastrointestinal side effects, most commonly oily stools, increased bowel frequency, and urgent need to open bowels. These effects are directly linked to dietary fat intake - keeping meals low in fat (approximately 15g per meal) significantly reduces side effects while maintaining effectiveness. Most patients find side effects decrease as they adapt their diet. Taking a daily multivitamin at bedtime helps replace fat-soluble vitamins that may be reduced during treatment.
Start Your Weight Management Journey Today
Whether you choose cost-effective generic orlistat or prefer branded Xenical, both offer identical clinical support for weight management when used alongside lifestyle changes. Complete your online consultation now and use code EDM10 for 10% off your first and future orders. Our UK-licensed prescribers will assess your suitability and, if appropriate, your medication will be dispensed and dispatched within 24 hours.


