Generic vs Branded: Making Your Purchase Decision
How Does Orlistat Work on Existing Fat?
Orlistat works by blocking lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. However, it's important to understand that orlistat does not work on existing body fat stores. Instead, it reduces the amount of new fat calories absorbed from meals, which can support weight management when combined with a reduced-calorie, lower-fat diet and regular exercise.
Orlistat 120mg vs Xenical 120mg: The Facts
Both products contain identical 120mg doses of the active ingredient orlistat. Generic orlistat offers the same clinical effect as branded Xenical at a significantly lower cost. A 4-week supply of generic orlistat costs £32.99 (£29.69 with EDM10), whilst Xenical costs £42.99 (£38.69 with EDM10) - saving you approximately £9 monthly by choosing the generic option.
Which Should You Buy?
Your choice depends primarily on budget and personal preference. Generic orlistat provides identical fat-blocking effects at the lowest price point. Some patients prefer branded Xenical for the reassurance of the original formulation, though both undergo the same rigorous UK regulatory standards. Both require prescription following clinical assessment by our UK-licensed prescribers.
Alternative: Alli 60mg
For those seeking a lower-strength option, Alli 60mg contains half the dose of prescription orlistat. Available from £26.09 for 4 weeks with EDM10, Alli may cause fewer gastrointestinal side effects but blocks a smaller proportion of dietary fat compared to the 120mg prescription options.
Order Process and Delivery
Complete our online health questionnaire for review by qualified UK-licensed prescribers. If clinically appropriate, your prescription will be dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly to your address with next-day delivery available. All orders qualify for 10% discount with code EDM10.
Managing Treatment Costs
Longer treatment periods offer better value. A 12-week supply of generic orlistat costs £86.39 with EDM10 compared to £116.09 for Xenical - total savings of nearly £30 over three months. Most patients find the initial 4-8 week period helpful for assessing tolerance before committing to longer supplies.


