Which Should You Choose: Generic or Branded?
Orlistat vs Xenical: The Clinical Facts
Generic orlistat 120mg and branded Xenical 120mg are clinically equivalent medications containing identical active ingredients at the same dose. Both work by inhibiting lipase enzymes in the gut, blocking approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through the digestive system. Xenical is manufactured by Roche, whilst generic orlistat comes from various licensed manufacturers - but the clinical effect remains identical.
Price Comparison: Significant Savings Available
Generic orlistat offers substantial cost savings versus branded Xenical. A 4-week supply (84 capsules) costs £32.99 for generic orlistat versus £42.99 for Xenical - that's nearly £10 monthly savings. With our EDM10 discount code, generic orlistat costs just £29.69 compared to £38.69 for Xenical. Over 12 weeks, you'll save £30+ choosing generic orlistat at £86.39 versus Xenical at £116.09.
Best Diet for Both Orlistat and Xenical
Whether you choose generic orlistat or branded Xenical, the dietary requirements are identical. Keep each main meal to approximately 15g fat or less to minimise gastrointestinal side effects. Spread your daily fat intake evenly across three meals, ensuring no more than 30% of daily calories come from fat. High-fat meals significantly increase the likelihood of oily stools, urgency, and other gut-related side effects with both medications.
Both medications work best alongside a reduced-calorie, lower-fat diet combined with regular physical activity. Consider taking a daily multivitamin at bedtime, as both orlistat and Xenical may reduce absorption of fat-soluble vitamins A, D, E, and K.
Alli 60mg: The Lower-Strength Alternative
For those preferring a gentler introduction, Alli 60mg contains half the orlistat dose of prescription-strength options. At £26.09 for a 4-week supply with EDM10, Alli offers a middle ground between over-the-counter accessibility and prescription strength. However, the fat-blocking effect is proportionally reduced compared to 120mg options.
Making Your Decision
Most patients choose generic orlistat 120mg for the cost savings without sacrificing clinical effectiveness. Some prefer branded Xenical for brand recognition, but both require the same low-fat dietary approach and produce identical results. Your prescriber can help determine which option suits your preferences and budget following clinical assessment.
Order Today from EverydayMeds
Complete your online health questionnaire for review by our UK-licensed prescribers. If approved, we'll dispense and dispatch your chosen medication from our GPhC-registered Leicester pharmacy with next day delivery. Use code EDM10 for 10% off every order. Start your weight management journey with confidence, backed by professional clinical support and regulated UK pharmaceutical supply.


