Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Key Facts
Both orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. The clinical effect is equivalent—both may help reduce absorption of approximately one third of dietary fat when used alongside a reduced-calorie, lower-fat diet. The primary difference lies in branding and cost, making this largely a budget decision.
Pricing Comparison: Orlistat vs Xenical
Generic orlistat offers significant savings over branded Xenical. For a 4-week supply (84 capsules), orlistat costs £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10)—saving you approximately £9 per month. Over 12 weeks, orlistat costs £95.99 (£86.39 with EDM10) versus Xenical at £128.99 (£116.09 with EDM10), representing savings of over £29.
Why Choose Generic Orlistat 120mg?
Most patients choose generic orlistat for its cost-effectiveness without compromising clinical outcomes. Manufactured to identical standards as branded versions, generic orlistat delivers the same lipase inhibition mechanism that blocks approximately one third of dietary fat absorption. Available from 2-week supplies (£16.89, £15.20 with EDM10) through to 12-week supplies, providing flexibility for your weight management journey.
When Patients Choose Xenical
Some patients prefer branded Xenical, manufactured by Roche, often citing brand familiarity or previous positive experiences. Whilst clinically equivalent to generic orlistat, Xenical carries premium pricing. For those prioritising brand preference over cost savings, Xenical remains an excellent choice for weight management support.
Alli 60mg: The Lower-Strength Alternative
For those seeking a lower-dose option, Alli 60mg provides half the strength of prescription orlistat. At £28.99 for 4 weeks (£26.09 with EDM10), Alli may suit those preferring a gentler introduction to orlistat treatment, though clinical effects are proportionally reduced compared to 120mg formulations.
Online Prescription Process
Both orlistat and Xenical require prescription following clinical assessment by our UK-licensed prescribers. Complete our online health questionnaire covering medical history, current medications, and BMI information. Following prescriber review and approval, your chosen medication is dispensed from our GPhC-registered Leicester pharmacy with next-day delivery across the UK. Use code EDM10 for 10% off every order.


