Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Key Facts
When comparing orlistat and Xenical for weight management, the most important fact is that both contain exactly the same active ingredient at the same dose - orlistat 120mg. This means they work identically in your body, blocking approximately one third of dietary fat absorption to support weight management alongside a reduced-calorie, lower-fat diet.
Generic orlistat 120mg capsules cost £32.99 for a 4-week supply (£29.69 with EDM10), while branded Xenical 120mg costs £42.99 for the same period (£38.69 with EDM10). Over a 12-week treatment course, choosing generic orlistat saves approximately £30 compared to Xenical - with identical clinical effects.
Price Comparison: Orlistat vs Xenical
Generic orlistat offers excellent value without compromising on quality or effectiveness. Our pricing includes the prescription and clinical assessment:
Orlistat 120mg (Generic): 2 weeks £15.20, 4 weeks £29.69, 8 weeks £57.59, 12 weeks £86.39 (all prices with EDM10 discount)
Xenical 120mg (Branded): 2 weeks £19.35, 4 weeks £38.69, 8 weeks £78.29, 12 weeks £116.09 (all prices with EDM10 discount)
Both products require prescription following clinical assessment by our UK-licensed prescribers. The online consultation process is identical regardless of which option you choose.
Consider Alli 60mg for Lower-Strength Option
If you prefer starting with a lower dose, Alli 60mg offers half the strength of prescription orlistat. While less potent than 120mg products, Alli may be suitable for those wanting a gentler introduction to orlistat treatment. Alli costs £26.09 for a 4-week supply with EDM10.
How Both Products Work
Whether you choose orlistat or Xenical, the mechanism is identical. Both work in your digestive system by inhibiting lipase enzymes that break down dietary fat. This prevents approximately one third of the fat you eat from being absorbed, with the unabsorbed fat passing naturally through your body. Neither product acts as a brain-based appetite suppressant - they work locally in the gut.
Making Your Decision
Most patients choose generic orlistat for the cost savings, especially for longer treatment courses. Some prefer branded Xenical for personal preference. Clinically, there is no difference in effectiveness, side effects, or dosing between the two 120mg options.
Both products must be used alongside a reduced-calorie, lower-fat diet with no more than approximately 15g fat per meal to minimise gastrointestinal side effects and maximise effectiveness.
Order Online with Prescription Included
Complete our online health questionnaire for clinical assessment by UK-licensed prescribers. If treatment is appropriate for you, we'll dispense and dispatch your chosen medication with next day delivery available. Use code EDM10 for 10% off every order from our GPhC-registered pharmacy in Leicester.


