Compare Orlistat vs Xenical: Make Your Choice Today
Orlistat vs Xenical: The Key Facts
Generic orlistat 120mg and branded Xenical 120mg contain exactly the same active ingredient at identical doses. Both work by inhibiting lipase enzymes in your digestive system, blocking approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body, which may support weight management alongside a reduced-calorie, lower-fat diet. Clinically, there is no difference in effectiveness—your choice comes down to personal preference and budget.
Price Comparison: Significant Savings with Generic
Generic orlistat offers substantial cost savings. A 4-week supply (84 capsules) costs £32.99, or £29.69 with our EDM10 discount code. The same period with branded Xenical costs £42.99, or £38.69 with EDM10—that's approximately £9 extra monthly. Over a 12-week treatment period, you could save around £30 by choosing generic orlistat (£86.39 vs £116.09 with discount). Both require the same online clinical assessment by our UK-licensed prescribers.
Gallstone Considerations for Both Products
Whether you choose orlistat or Xenical, weight management support may increase gallstone risk in susceptible individuals. This applies equally to both formulations since they contain identical active ingredients. During your online consultation, our prescriber will assess your individual risk factors, including any history of gallbladder problems. Some patients may benefit from starting with lower-strength Alli 60mg (£26.09 for 4 weeks with EDM10) to minimise potential complications while still supporting weight management.
Which Should You Buy?
Choose generic orlistat if cost-effectiveness is your priority—you'll receive the same clinical benefit at a lower price. Choose Xenical if you prefer branded medication from Roche. Both require taking one capsule three times daily with fat-containing meals, and both work best when you limit fat intake to approximately 15g per meal. Remember, gastrointestinal side effects are more likely with high-fat meals regardless of which product you select.
Order Process: Same for Both Options
Complete our confidential online health questionnaire covering your medical history, current BMI, and weight management goals. Our UK-licensed prescriber will review your information and, if clinically appropriate, issue a prescription. We'll dispense your chosen treatment from our GPhC-registered pharmacy in Leicester and dispatch for next-day delivery. Use code EDM10 for 10% off your order—applicable to orlistat, Xenical, and Alli.


