Which Should You Buy: Orlistat or Xenical?
Orlistat vs Xenical: The Facts
When deciding whether to buy Xenical online or choose generic Orlistat, understanding the facts helps you make an informed choice. Both Orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. Clinically, they work identically — both block approximately one third of dietary fat absorption when taken with meals containing fat.
The primary difference is cost. Generic Orlistat offers the same clinical effect as branded Xenical at a lower price point. A 4-week supply of Orlistat costs £32.99 (£29.69 with EDM10), whilst Xenical costs £42.99 (£38.69 with EDM10) — saving you over £100 annually with generic Orlistat.
Orlistat 120mg: Best Value Option
Generic Orlistat 120mg provides excellent value for money without compromising clinical effectiveness. Available in multiple pack sizes: 2 weeks (42 capsules) for £15.20 with EDM10, 4 weeks (84 capsules) for £29.69, 8 weeks (168 capsules) for £57.59, and 12 weeks (252 capsules) for £86.39. Each capsule contains 120mg orlistat, taken three times daily with main meals containing fat.
Orlistat works by inhibiting lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body. The medication must be used alongside a reduced-calorie, lower-fat diet and increased physical activity for optimal results.
Xenical 120mg: Branded Option
Xenical, manufactured by Roche, offers the same orlistat 120mg formulation as generic versions. Some patients prefer branded medications, and Xenical remains a popular choice. Pricing starts from £19.35 for 2 weeks with EDM10, £38.69 for 4 weeks, £78.29 for 8 weeks, and £116.09 for 12 weeks. The clinical effect, dosing schedule, and side effect profile are identical to generic Orlistat.
Alli 60mg: Lower-Strength Alternative
For those preferring a lower-strength starting point, Alli 60mg contains half the orlistat dose of prescription-strength options. Priced from £26.09 for 4 weeks with EDM10, Alli may cause milder gastrointestinal side effects due to the reduced dose, though clinical effectiveness is correspondingly lower.
Online Prescription Process
Both Orlistat and Xenical require prescription-only access through clinical assessment. EverydayMeds' online consultation involves completing a medical questionnaire reviewed by UK-licensed prescribers. If clinically appropriate, your prescription is processed and medication dispensed by our GPhC-registered Leicester pharmacy. Next day delivery ensures quick access to your chosen treatment.
Managing Treatment Effectively
Whether you choose Orlistat or Xenical, success depends on dietary compliance. Keep meal fat content low (approximately 15g per meal) to minimise gastrointestinal side effects. Take a multivitamin supplement at bedtime, as orlistat may reduce fat-soluble vitamin absorption. Most side effects are gastrointestinal and directly related to dietary fat intake — they indicate the medication is working.
Making Your Decision
Choose generic Orlistat for maximum value and identical clinical benefits, or select Xenical if you prefer branded medication. Both options are available through our secure online consultation process. Use code EDM10 for 10% off every order, applicable to both new and returning customers.


