Which Should You Buy: Generic or Branded?
Orlistat vs Xenical: Identical Effect, Different Price
When choosing between orlistat 120mg and Xenical 120mg, you're comparing two clinically equivalent medicines. Both contain exactly the same active ingredient (orlistat) at the same 120mg dose, working by blocking approximately one third of dietary fat absorption in your digestive system. The primary difference lies in cost and branding preferences.
Generic Orlistat 120mg - Best Value Option
Generic orlistat 120mg provides identical clinical benefits at significantly lower cost. Our 4-week supply (84 capsules) costs £32.99, reduced to £29.69 with discount code EDM10. This prescription-only medicine offers the same fat-blocking mechanism as branded alternatives, making it the cost-effective choice for long-term weight management programmes alongside reduced-calorie, lower-fat diets.
Xenical 120mg - Branded Option
Xenical, manufactured by Roche, contains the same orlistat 120mg formula with identical clinical effect. Our 4-week supply costs £42.99 (£38.69 with EDM10). Some patients prefer the branded option, though it provides no clinical advantage over generic orlistat. Both require the same online clinical assessment and prescription approval from UK-licensed prescribers.
Alli 60mg - Lower Strength Alternative
Alli 60mg offers half the dose of prescription-strength orlistat, blocking a smaller proportion of dietary fat. At £54.99 for 8 weeks (£49.49 with EDM10), it may suit those preferring a gentler starting point, though clinical effectiveness is correspondingly reduced compared to 120mg formulations.
Your Savings Comparison
Monthly savings choosing generic orlistat over Xenical are substantial. For 12-week supplies, orlistat costs £95.99 (£86.39 with EDM10) versus Xenical at £128.99 (£116.09 with EDM10) - saving nearly £30 for identical clinical outcomes. Both medicines require three capsules daily with main meals containing fat, working best when dietary fat intake stays around 15g per meal.
Online Prescription Process
Both orlistat and Xenical require prescription following online clinical assessment. Our UK-licensed prescribers review your medical history, current medications, and BMI information to determine treatment suitability. Subject to prescriber approval, medicines are dispensed by our GPhC-registered Leicester pharmacy with next day delivery across the UK. The prescription consultation is included - no separate GP appointment needed.
Which Treatment to Choose
For identical clinical effect at lower cost, choose generic orlistat 120mg. If you prefer branded medicines, Xenical provides the same outcomes with premium pricing. Both work by inhibiting lipase enzymes in your gut, preventing absorption of approximately one third of dietary fat when used alongside structured weight management programmes including reduced-calorie, lower-fat diets and increased physical activity.


