Why Understanding Orlistat's Mechanism Matters for Results
How Orlistat Blocks Fat Absorption
Orlistat works through a targeted mechanism that inhibits lipase enzymes in your digestive system. These enzymes normally break down dietary fat so it can be absorbed into your body. When orlistat blocks approximately one third of these enzymes, that proportion of fat passes through your system undigested. This isn't a stimulant affecting your brain - it's a local action in your gut that directly reduces calorie absorption from fat.
Timing Orlistat with Meals: Before, During, or After
Take orlistat immediately before, during, or up to one hour after each main meal containing fat. This timing ensures the medication is present when lipase enzymes begin breaking down dietary fat. If you skip a meal or eat a fat-free meal, you can skip that dose. Our orlistat 120mg costs £32.99 for 84 capsules (4-week supply), reduced to £29.69 with code EDM10.
Why This Mechanism Proves Orlistat Works
The fat-blocking mechanism explains why orlistat may cause gastrointestinal side effects - they're actually proof the medication is working. Unabsorbed fat has to leave your body somehow, which can cause oily stools or urgent bowel movements, especially with high-fat meals. Keep dietary fat low (approximately 15g per meal) to minimise these effects while maximising weight management support.
Orlistat vs Xenical: Same Mechanism, Different Price
Both orlistat 120mg and Xenical 120mg contain identical active ingredients and work through the same fat-blocking mechanism. Generic orlistat offers the same clinical effect as branded Xenical but costs significantly less. Compare 12-week supplies: orlistat £95.99 (£86.39 with EDM10) versus Xenical £128.99 (£116.09 with EDM10). That's over £25 savings with the generic option.
Getting Started with Orlistat Through EverydayMeds
Our UK-licensed prescribers assess your suitability through an online clinical consultation. If orlistat is appropriate for your weight management goals, we'll issue a private prescription and dispatch from our GPhC-registered pharmacy in Leicester. Choose from 2-week starter packs (£16.89) up to 12-week supplies (£95.99). All prices include prescription, consultation, and next day tracked delivery.
Order Orlistat Today
Now you understand how orlistat's fat-blocking mechanism works, you can make an informed decision about starting treatment. Complete your online assessment today and receive orlistat with 10% off using code EDM10. Our qualified prescribers are ready to review your application and help you begin effective weight management support.


