Why Understanding Orlistat's Mechanism Matters for Results
How Orlistat Works in Your Body
Orlistat works by blocking approximately one third of the fat you eat from being absorbed into your body. It inhibits lipase enzymes in your digestive system that normally break down dietary fat. When these enzymes are blocked, the unabsorbed fat passes naturally through your system. This proven mechanism means orlistat acts locally in your gut, not your brain - making it different from appetite suppressants. Generic orlistat 120mg (£32.99 for 84 capsules, £29.69 with EDM10) and branded Xenical 120mg (£42.99 for 84 capsules, £38.69 with EDM10) use this identical mechanism.
When to Take Orlistat for Maximum Effect
Take one orlistat capsule with each main meal containing fat - up to three times daily. You can take it immediately before, during, or up to one hour after eating. If you miss a meal or eat a meal with no fat, skip that dose. This timing ensures the medication works when your body needs to process dietary fat. The 42-capsule pack (£16.89, £15.20 with EDM10) provides a 2-week supply at this standard dosing schedule.
Why the Mechanism Proves Orlistat Works
Orlistat's fat-blocking mechanism is clinically proven and directly observable. When approximately one third of dietary fat passes through unabsorbed, you may notice oily stools - this shows the medication is working. The mechanism works consistently whether you choose generic orlistat or Xenical, as both contain identical 120mg orlistat. For longer treatment, our 168-capsule packs provide 8 weeks' supply (orlistat £63.99, £57.59 with EDM10; Xenical £86.99, £78.29 with EDM10).
Combining Mechanism Knowledge with Diet
Understanding how orlistat blocks fat absorption helps you eat appropriately. Keep meals to approximately 15g fat each to minimise side effects while maximising results. The medication can only block fat that's present in your meal - so a reduced-calorie, lower-fat diet remains essential. This approach works with orlistat's mechanism rather than against it. Our 12-week supplies support longer-term treatment (252 capsules: orlistat £95.99, £86.39 with EDM10).
Start Treatment Today with Confidence
Now you understand exactly how orlistat works and when to take it, you can start treatment with confidence. Our online clinical assessment takes minutes, and following prescriber approval, we'll dispatch your medication from our GPhC-registered Leicester pharmacy. Use code EDM10 for 10% off every order. Whether you choose cost-effective generic orlistat or branded Xenical, you're getting the same proven fat-blocking mechanism that helps support weight management alongside dietary changes.
