Choose Your Orlistat Supply: Signs It's Working
Understanding How Orlistat Works in Your System
Orlistat works by blocking approximately one third of dietary fat absorption in your digestive system. Within days of starting treatment, you may notice gastrointestinal effects when eating meals containing fat - these are actually signs the medication is working. Our supply options help you maintain consistent treatment whilst monitoring progress.
2-Week Starter Supply: Initial Assessment Period
Perfect for first-time users wanting to assess tolerance. Generic orlistat 42 capsules costs £16.89 (£15.20 with EDM10), while Xenical 42 capsules costs £21.50 (£19.35 with EDM10). This allows you to evaluate how your body responds before committing to longer treatment periods. Order your 2-week starter supply today.
4-Week Supply: Establishing Routine
Our most popular choice for building consistent habits. Orlistat 84 capsules costs £32.99 (£29.69 with EDM10), Xenical 84 capsules costs £42.99 (£38.69 with EDM10), and Alli 42 capsules costs £28.99 (£26.09 with EDM10). Four weeks provides sufficient time to establish dietary changes and monitor initial progress markers.
8-Week Supply: Significant Savings
Ideal for committed weight management programmes. Orlistat 168 capsules costs £63.99 (£57.59 with EDM10), saving £1.39 versus two 4-week orders. Xenical 168 capsules costs £86.99 (£78.29 with EDM10), while Alli 84 capsules costs £54.99 (£49.49 with EDM10). Eight weeks allows meaningful progress assessment alongside a reduced-calorie, lower-fat diet.
12-Week Supply: Maximum Value
Best value for long-term treatment commitment. Orlistat 252 capsules costs £95.99 (£86.39 with EDM10), saving £2.68 versus three 4-week supplies. Xenical 252 capsules costs £128.99 (£116.09 with EDM10), while Alli 252 capsules costs £129.99 (£116.99 with EDM10). Twelve weeks provides substantial treatment duration for sustained weight management support.
Signs Your Treatment is Working
Gastrointestinal effects like oily stools or increased bowel frequency indicate orlistat is blocking fat absorption as intended. These effects typically reduce as you adapt your diet to lower fat content. Combined with a reduced-calorie diet and increased physical activity, you may notice gradual weight changes over weeks rather than days. Consistent medication taking with each main meal containing fat maximises effectiveness.
Choosing Your Optimal Supply Length
New users often start with 2 or 4-week supplies to assess tolerance, then progress to 8 or 12-week packs for better value. All supplies require clinical assessment by our UK-licensed prescribers. Simply complete our online health questionnaire for prescriber review. Order your chosen supply today for next day delivery across the UK.


