Compare Orlistat vs Xenical Prices and Options
Orlistat vs Xenical: Identical Clinical Effect
Generic orlistat 120mg and branded Xenical 120mg contain exactly the same active ingredient at identical doses. Both work by inhibiting lipase enzymes in your digestive system, blocking approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body, which may help support weight management when used alongside a reduced-calorie, lower-fat diet and increased physical activity.
Cost Comparison: Orlistat vs Xenical Pricing
Generic orlistat 120mg offers substantial savings compared to branded Xenical. Our 4-week supply costs £32.99 (£29.69 with EDM10) for orlistat versus £42.99 (£38.69 with EDM10) for Xenical - saving approximately £9 per month. For 12-week supplies, choose orlistat at £95.99 (£86.39 with EDM10) compared to Xenical at £128.99 (£116.09 with EDM10), saving over £30 per treatment cycle. Both options require the same clinical assessment and provide identical therapeutic benefits.
Alternative Option: Alli 60mg
Alli contains half the dose of orlistat at 60mg per capsule. This lower-strength option blocks a smaller proportion of dietary fat compared to prescription-strength 120mg formulations. Alli 60mg costs £54.99 for 8 weeks (£49.49 with EDM10) and may be suitable for those preferring a gentler starting approach to fat absorption reduction.
Online Prescription Process
Both orlistat 120mg and Xenical 120mg require prescription following clinical assessment. Complete our online health questionnaire covering your medical history, current medications, and BMI information. Our UK-licensed prescribers review your consultation and issue prescriptions where clinically appropriate. Treatment suitability is assessed individually - not everyone will be eligible for prescription weight loss medication.
How Orlistat and Xenical Work
Whether you choose generic orlistat or branded Xenical, the mechanism remains identical. Take one 120mg capsule with each main meal containing fat, up to three times daily. The medication works locally in your gut, not your brain, by preventing approximately one third of dietary fat from being digested. This can support calorie reduction when combined with a structured lower-fat diet plan.
Managing Side Effects
Both orlistat and Xenical may cause gastrointestinal side effects, particularly when eating high-fat meals. Common effects include oily stools, increased bowel movements, and flatulence with discharge. These side effects can be minimised by keeping meal fat content low - approximately 15g fat per meal. Most patients find side effects reduce as they adapt their diet to lower fat intake.
Next Steps: Start Your Assessment
Ready to compare orlistat vs Xenical for your weight management goals? Begin with our online clinical assessment to determine treatment suitability. Our prescribers will recommend the most appropriate option based on your individual circumstances and preferences. All medications are dispensed by our GPhC-registered pharmacy with secure next day delivery across the UK.


