Which Should You Buy: Orlistat or Xenical?
Orlistat vs Xenical: The Key Differences
When comparing orlistat and Xenical, the most important fact is that both contain exactly the same active ingredient at the same 120mg dose. Xenical is the branded version manufactured by Roche, whilst orlistat is the generic equivalent. Clinically, they work identically - blocking approximately one third of dietary fat absorption through lipase enzyme inhibition in the gut.
The primary difference is cost. Generic orlistat 120mg costs £29.69 for a 4-week supply with code EDM10, compared to £38.69 for branded Xenical - saving you over £9 monthly. For a 12-week course, you'll save £29.70 choosing generic orlistat (£86.39) over Xenical (£116.09).
What About Alli 60mg?
Alli contains half the dose at 60mg orlistat per capsule. This lower strength blocks a smaller proportion of dietary fat compared to prescription-strength 120mg products. Alli costs £26.09 for 4 weeks with EDM10, making it the most affordable option, though clinically less potent than the 120mg prescription versions.
Clinical Assessment Required
Both orlistat 120mg and Xenical 120mg are prescription-only medicines requiring clinical assessment by a UK-licensed prescriber. Our online consultation process involves completing a medical questionnaire covering your BMI, health history, and current medications. Treatment may be suitable for adults with BMI 30+ or BMI 28+ with weight-related health conditions like type 2 diabetes or high blood pressure.
How to Choose Between Orlistat and Xenical
Your choice depends on personal preference and budget. Generic orlistat offers identical clinical benefits at a lower cost - ideal for those prioritising value. Some patients prefer branded Xenical for the reassurance of the original manufacturer. Both must be used alongside a reduced-calorie, lower-fat diet and regular physical activity.
Order online today with clinical assessment included. Use code EDM10 for 10% off, with next day delivery from our GPhC-registered Leicester pharmacy. No separate GP appointment needed.
Complete Pricing Comparison
Generic Orlistat 120mg: 2 weeks £15.20, 4 weeks £29.69, 8 weeks £57.59, 12 weeks £86.39 (with EDM10). Branded Xenical 120mg: 2 weeks £19.35, 4 weeks £38.69, 8 weeks £78.29, 12 weeks £116.09 (with EDM10). Alli 60mg: 4 weeks £26.09, 8 weeks £49.49, 12 weeks £116.99 (with EDM10).


