Compare Orlistat vs Xenical Prices & Choose
Orlistat vs Xenical: The Key Difference is Price
The most important fact when choosing between orlistat and Xenical is that both contain exactly the same active ingredient at the same 120mg dose. Clinically, they work identically - both block approximately one third of dietary fat absorption when taken alongside a reduced-calorie, lower-fat diet. The key difference is cost, with generic orlistat offering substantial savings over branded Xenical.
Generic Orlistat 120mg Pricing
Our most popular choice for prescription weight loss medication. Generic orlistat 120mg capsules cost £32.99 for 4 weeks (84 capsules), reduced to £29.69 with discount code EDM10. Longer supplies offer better value: 8 weeks costs £57.59 with EDM10, whilst 12 weeks costs £86.39 with EDM10. Same clinical effect as Xenical at significantly lower cost.
Branded Xenical 120mg Pricing
Xenical is the original branded version manufactured by Roche. It costs £42.99 for 4 weeks (84 capsules), reduced to £38.69 with code EDM10. Extended supplies: 8 weeks costs £78.29 with EDM10, and 12 weeks costs £116.09 with EDM10. Some patients prefer branded medication, though the active ingredient orlistat works identically to generic versions.
Alli 60mg: Lower-Strength Alternative
Alli contains 60mg orlistat - half the prescription dose. At £28.99 for 4 weeks (reduced to £26.09 with EDM10), it offers a lower-strength starting option. Alli blocks a smaller proportion of dietary fat compared to prescription 120mg strength, but may cause fewer gastrointestinal side effects for some users.
Which Should You Choose?
For identical clinical results at lower cost, generic orlistat 120mg represents excellent value. Patients choosing Xenical pay approximately £9 extra monthly for the branded version with no additional clinical benefit. Alli 60mg suits those preferring lower-strength treatment. All options require clinical assessment by a UK-licensed prescriber before prescription can be issued.
How All Three Products Work
Orlistat, Xenical and Alli all work by inhibiting lipase enzymes in the gut, preventing approximately one third of dietary fat from being absorbed. Unabsorbed fat passes naturally through the body. This mechanism reduces calorie intake from fat when used alongside a reduced-calorie, lower-fat diet and increased physical activity. Treatment works best when meals contain no more than 15g fat each.
Order Your Preferred Option Today
Complete our online clinical assessment to determine suitability for orlistat treatment. Our UK-licensed prescribers review applications and issue prescriptions where clinically appropriate. All medication is dispensed by our GPhC-registered Leicester pharmacy with next day delivery available. Use code EDM10 for 10% off every order - new and returning customers.


