Orlistat vs Xenical: Which Should You Choose?
Orlistat vs Wegovy: Key Differences
Orlistat and Wegovy are entirely different medications for weight management. Orlistat works locally in the gut by blocking approximately one third of dietary fat absorption through lipase enzyme inhibition. Wegovy (semaglutide) is an injectable GLP-1 receptor agonist that acts on the brain to reduce appetite. Both require prescription and clinical assessment, but have different mechanisms, administration methods, and side effect profiles.
Orlistat 120mg vs Xenical 120mg: Same Effect, Different Price
The primary difference between generic orlistat 120mg and branded Xenical 120mg is cost - both contain identical active ingredients at the same strength. Generic orlistat offers significant savings: 4-week supply costs £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10). This represents approximately £9 monthly savings whilst receiving the same clinical effect. Both versions work by blocking approximately one third of dietary fat absorption when taken with meals.
Available Pack Sizes and Pricing
We stock multiple pack sizes to suit different treatment durations. Generic orlistat 120mg: 2 weeks (42 capsules) £15.20, 4 weeks (84 capsules) £29.69, 8 weeks (168 capsules) £57.59, or 12 weeks (252 capsules) £86.39 with EDM10. Branded Xenical 120mg: 2 weeks £19.35, 4 weeks £38.69, 8 weeks £78.29, or 12 weeks £116.09 with EDM10. Alli 60mg (lower strength) is also available from £26.09 for 4 weeks with EDM10.
Who Can Take Orlistat or Xenical?
Both orlistat and Xenical may be suitable for adults with BMI 30kg/m² or above, or BMI 28kg/m² with weight-related health conditions like type 2 diabetes or high blood pressure. Treatment must be used alongside a reduced-calorie, lower-fat diet and increased physical activity. Our UK-licensed prescribers assess individual suitability through online consultation, reviewing medical history and current medications before prescribing.
How to Order Online
Complete our online health questionnaire for clinical assessment by a UK-licensed prescriber. If treatment is appropriate, your prescription will be dispensed by our GPhC-registered pharmacy in Leicester and dispatched for next-day delivery. Use code EDM10 for 10% off every order. The prescription is included in the price - no separate GP appointment required. Choose between generic orlistat for maximum value or branded Xenical based on your preference.
