The Science Behind Viagra's Effectiveness
What Happens During Normal Sexual Function
When sexually aroused, your body naturally releases nitric oxide, which triggers the production of cyclic guanosine monophosphate (cGMP). This chemical messenger relaxes smooth muscle in blood vessels, allowing increased blood flow to the penis. However, an enzyme called phosphodiesterase type 5 (PDE5) breaks down cGMP, which can reduce blood flow and make maintaining an erection difficult.
How Sildenafil Blocks the PDE5 Enzyme
Viagra's active ingredient, sildenafil citrate, works as a selective PDE5 inhibitor. By blocking this enzyme, sildenafil allows cGMP levels to remain elevated for longer periods. This means blood vessels can stay relaxed and dilated, maintaining improved blood flow to the penis during sexual activity. The medication doesn't create arousal itself but enhances your body's natural erectile response when sexually stimulated.
Timing and Duration of Effects
Most men find Viagra becomes effective within 30-60 minutes of taking it, though this can vary based on individual factors like metabolism and food intake. Fatty meals may delay absorption, so taking the medication on an empty stomach or after a light meal often provides more predictable results. The effects typically last 4-6 hours, during which time you may find it easier to achieve and maintain erections when aroused.
Available Treatment Options
EverydayMeds offers both Viagra (the original branded version) and sildenafil (the generic alternative) following an online consultation. Both contain the same active ingredient and work identically, but sildenafil provides a more cost-effective option. Standard doses include 25mg, 50mg, and 100mg tablets, with most men starting on the 50mg strength. Your prescriber will recommend the most suitable dose based on your health assessment and needs.
Important Safety Considerations
Sildenafil can interact dangerously with certain medications, particularly nitrates used for chest pain (such as GTN spray or isosorbide tablets). This combination can cause a severe drop in blood pressure. The medication may also not be suitable for men with certain heart conditions, severe liver problems, or very low blood pressure. A thorough medical assessment helps ensure safe and appropriate treatment.
Maximising Treatment Effectiveness
To get the best results from your treatment, take your medication as prescribed and avoid excessive alcohol, which can reduce effectiveness. Remember that sexual stimulation is still required - sildenafil enhances natural function rather than creating artificial erections. If you don't see improvements with your initial dose, speak to your prescriber about adjusting the strength rather than taking additional tablets.
