Complete Aciclovir Usage Guide for Cold Sores
Standard Dosing Instructions
For cold sores, aciclovir tablets are typically prescribed as 400mg taken five times daily for 5 days. The key to effective treatment is starting as early as possible - ideally at the first sign of symptoms such as tingling, itching, or burning around the lip area. Each dose should be spaced approximately 4 hours apart during waking hours.
How to Take Aciclovir Tablets
Swallow aciclovir tablets whole with a full glass of water. The medication can be taken with or without food, though taking it with food may help reduce potential stomach upset. Never crush, chew, or break the tablets unless specifically advised by your healthcare provider. If you have difficulty swallowing tablets, dispersible formulations may be available.
Timing and Treatment Duration
Begin treatment within 24-48 hours of the first symptoms for optimal effectiveness. Starting treatment after blisters have already formed may be less effective. Continue taking aciclovir for the full prescribed duration, typically 5 days, even if symptoms begin to improve. Stopping treatment early may allow the virus to continue replicating.
Important Considerations
Maintain adequate hydration whilst taking aciclovir, as the medication is processed through the kidneys. If you miss a dose, take it as soon as you remember, but skip it if it's nearly time for your next dose - never double dose. Be aware that aciclovir treats symptoms but doesn't cure the herpes virus. EverydayMeds offers aciclovir 400mg tablets alongside topical aciclovir cream for comprehensive cold sore management.
When to Seek Medical Advice
Contact your healthcare provider if cold sores don't improve after completing the course, if you experience frequent outbreaks, or if you develop signs of secondary bacterial infection. Severe side effects, though uncommon, require immediate medical attention.






