How to Inject Wegovy: Injection Sites, Steps and Storage (November 2026)

01 · Where to inject

Where to inject Wegovy

Inject into the fatty areas of your thigh, tummy or upper arm. You can use the same area, but do not use the exact same spot each time.¹ Choosing a slightly different spot each week helps avoid redness, itching or small lumps under the skin.

02 · Support

Help with your first injection

If you are unsure about any step, contact our pharmacy team before you inject. Wegovy (semaglutide) is a prescription-only medicine, supplied only after an online consultation reviewed by a GPhC-registered prescriber. This page is information, not a substitute for medical advice. Always read the leaflet and instructions for use that come with your pen.

03 · Before you inject

Before you inject

• Check the pen is the strength you were prescribed and has not passed its expiry date.
• Check the medicine looks clear and colourless; do not use it if it is cloudy or has particles.
• Wash your hands and choose your injection spot.
• Attach a new needle, following the instructions for use.

04 · The injection

Giving the injection

Follow the step-by-step instructions for use in your pack, as pens differ. In general, you set the dose, insert the needle straight into the skin, press and hold the button until the dose is complete, then remove the needle. Do not rub the area afterwards. Put the used needle straight into a sharps bin; with us, needles and a sharps bin come with every injection order.

05 · Same day each week

Inject on the same day each week

Wegovy is a once-weekly injection, given on the same day each week. A phone reminder helps. If it is 5 days or less since you should have had your dose, inject as soon as you remember; if it is more than 5 days, skip the missed dose and take the next one on your usual day.¹

06 · The 7.2mg dose

Injecting the 7.2mg dose

When the 7.2mg dose was first approved, it was given as three separate 2.4mg injections on the same day, changing the needle between each; the injections can be in the same body area but should be at least 5cm apart.² A single-dose 7.2mg pen was approved in April 2026, so the full dose can be given in one injection.³ Follow the instructions for the pen you are supplied.

07 · Storage

Storing your pen

Keep your injection pen in the fridge until you are ready to use it.¹ Do not freeze it, and keep it out of direct sunlight. For how long a pen can be kept out of the fridge once in use, check the leaflet that comes with it.

08 · Injection site reactions

Injection site reactions

Itchy or red skin where you inject is a common side effect and usually settles within a few days.¹ Rotating spots helps. If a reaction is large, painful or getting worse, contact the prescribing team. Our Wegovy side effects guide covers other side effects.