Why Understanding Orlistat's Mechanism Matters
How Orlistat Blocks Fat Absorption
Orlistat works by inhibiting lipase enzymes in your digestive system. These enzymes normally break down dietary fat so it can be absorbed into your body. When orlistat blocks approximately one third of these enzymes, the corresponding fat cannot be digested or absorbed. Instead, this unabsorbed fat passes naturally through your digestive system and is eliminated from your body.
Why This Mechanism Makes Orlistat Effective
Unlike appetite suppressants that work in the brain, orlistat acts locally in your gut. This targeted approach means it directly prevents approximately one third of dietary fat calories from entering your system. When combined with a reduced-calorie, lower-fat diet, this mechanism can significantly reduce your overall calorie intake from fat. Generic orlistat 120mg offers this proven mechanism from £32.99 for a 4-week supply (£29.69 with EDM10).
Same Mechanism Across All Orlistat Products
Whether you choose generic orlistat 120mg, branded Xenical 120mg, or lower-strength Alli 60mg, the mechanism remains identical - lipase enzyme inhibition. Generic orlistat provides the same fat-blocking effect as branded Xenical but costs significantly less. Our 12-week generic orlistat supply costs £95.99 (£86.39 with EDM10) compared to Xenical at £128.99 (£116.09 with EDM10) - saving you over £30.
What Happens When You Take Orlistat
Take one capsule with each main meal containing fat. The orlistat works immediately in that meal to block approximately one third of fat absorption. If you eat a meal with no fat, you can skip that dose as there's nothing for the medication to block. This meal-by-meal mechanism means you have control over how much the medication works based on your dietary choices.
Why Lower Fat Meals Improve Results
Understanding orlistat's mechanism explains why keeping fat intake low per meal is crucial. High-fat meals mean more unabsorbed fat passing through your system, leading to gastrointestinal side effects. Keep each meal to approximately 15g fat or less to minimise side effects while maximising the weight management benefits. This approach works whether you're taking prescription-strength orlistat or lower-dose Alli.
Order Your Orlistat Treatment Today
Now you understand exactly how orlistat works to block approximately one third of dietary fat absorption, you can make an informed treatment choice. Complete our online clinical assessment to get started. Our UK-licensed prescribers will review your suitability and, if appropriate, issue your prescription. All treatments are dispensed by our GPhC-registered pharmacy with next day delivery available. Use code EDM10 for 10% off every order.
