Why Orlistat's Proven Mechanism Makes It Effective
How Orlistat Blocks Fat Absorption
Orlistat works through a scientifically proven mechanism that targets fat digestion in your gut. Unlike appetite suppressants that act on the brain, orlistat inhibits lipase enzymes responsible for breaking down dietary fat. This local action in your digestive system blocks approximately one third of the fat you eat from being absorbed into your bloodstream. The unabsorbed fat passes naturally through your body, reducing the calories absorbed from dietary fat.
Why This Mechanism Proves Orlistat Works
The fat-blocking action provides visible proof that orlistat is working. When you eat meals containing fat whilst taking orlistat, you may notice oily stools or discharge - this is the blocked fat leaving your body naturally. This mechanism explains why orlistat must be taken with a reduced-calorie, lower-fat diet for best results and to minimise gastrointestinal side effects.
Generic Orlistat vs Xenical - Same Mechanism, Different Prices
Both generic orlistat 120mg and branded Xenical 120mg contain identical active ingredients and work through the same fat-blocking mechanism. Generic orlistat offers excellent value at £29.69 for 4 weeks (84 capsules) with EDM10, whilst Xenical costs £38.69 for the same supply. Both require prescription following clinical assessment by our UK-licensed prescribers.
Orlistat Dosing for Maximum Fat-Blocking Effect
Take one 120mg capsule three times daily with each main meal containing fat. The timing is crucial - take orlistat immediately before, during, or up to one hour after eating. If you skip a meal or eat a fat-free meal, you can skip that dose. This dosing schedule ensures optimal fat-blocking when you need it most.
Order Your Orlistat Treatment Today
Now you understand how orlistat's proven fat-blocking mechanism works, you can order with confidence. Our 2-week starter packs begin at £15.20 for generic orlistat or £19.35 for Xenical with code EDM10. Complete our online clinical assessment for review by UK-licensed prescribers, then receive next day delivery from our GPhC-registered Leicester pharmacy. Understanding the science behind orlistat proves why it's prescribed - order your treatment today.


