Understanding How Orlistat Works Before You Buy
How Orlistat Blocks Fat Absorption
Orlistat works by inhibiting lipase enzymes in your digestive system that normally break down dietary fat. When these enzymes are blocked, approximately one third of the fat you eat cannot be digested or absorbed into your body. This unabsorbed fat passes naturally through your system and is excreted. The mechanism is proof that orlistat works - it acts locally in your gut rather than affecting your brain or metabolism systemically.
Orlistat 120mg Pricing & Pack Sizes
Generic orlistat 120mg offers excellent value: 42 capsules (2 weeks) costs £16.89 or £15.20 with code EDM10, 84 capsules (4 weeks) costs £32.99 or £29.69 with EDM10, and 168 capsules (8 weeks) costs £63.99 or £57.59 with EDM10. The 252 capsule pack provides 12 weeks' supply for £95.99 or £86.39 with our 10% discount. All prescription orlistat requires clinical assessment by our UK-licensed prescribers.
Xenical vs Generic Orlistat - Same Mechanism, Different Cost
Xenical 120mg contains identical orlistat and works exactly the same way as generic versions. Both block approximately one third of dietary fat absorption through the same lipase inhibition mechanism. Xenical starts from £21.50 for 42 capsules (£19.35 with EDM10) while generic orlistat starts from £16.89 - saving you around £9 per month. The clinical effect is identical, so many patients choose generic orlistat for better value.
Why The Fat-Blocking Mechanism Matters
Understanding that orlistat blocks approximately one third of dietary fat helps explain why it works best with lower-fat meals. High-fat meals increase gastrointestinal side effects because more unabsorbed fat passes through your system. The mechanism also explains why orlistat must be taken with meals containing fat - if you skip a meal or eat fat-free food, you can skip that dose. This targeted approach makes orlistat different from appetite suppressants.
Alli 60mg - Half Strength Option
Alli contains 60mg orlistat - half the prescription strength. It works through the same fat-blocking mechanism but blocks a smaller proportion of dietary fat. Alli 60mg costs £28.99 for 42 capsules (4 weeks) or £26.09 with EDM10. While less potent than prescription-strength orlistat, some people prefer starting with the lower dose to assess tolerance.
Order Today - Fast UK Delivery
Now you understand how orlistat works by blocking approximately one third of dietary fat absorption, you can make an informed purchase decision. Complete our online clinical assessment to get your prescription from UK-licensed prescribers. We dispense from our GPhC-registered Leicester pharmacy with next day delivery. Use code EDM10 for 10% off every order - new and returning customers welcome.


