Orlistat vs Xenical: Drug Interactions & Which to Buy

pricing for mounjaro and wegovy weight loss

Orlistat 120mg and Xenical 120mg contain the same active ingredient and have identical drug interactions. Both may interact with warfarin, ciclosporin, and levothyroxine. The key difference is price: generic orlistat starts from £29.69 for 4 weeks vs Xenical at £38.69 with code EDM10. Both work by blocking approximately one third of dietary fat absorption. Following online clinical assessment by our UK-licensed prescribers, you can access either option through EverydayMeds' GPhC-registered pharmacy with next day delivery. Choose generic orlistat for better value or branded Xenical - both offer the same clinical effect.

  • Same drug interactions for both orlistat and Xenical 120mg
  • Generic orlistat from £29.69 vs Xenical £38.69 (4 weeks with EDM10)
  • Identical clinical effect - block approximately one third dietary fat
  • Next day delivery from GPhC-registered Leicester pharmacy
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Which Should You Buy: Orlistat or Xenical?

Drug Interactions: Orlistat vs Xenical Are Identical

Both orlistat 120mg and Xenical 120mg contain the same active ingredient, so their drug interactions are identical. Key medications that may interact include warfarin (anticoagulant), ciclosporin (immunosuppressant), and levothyroxine (thyroid medication). If you're taking any of these, discuss with your prescriber during your online consultation. Antiepileptic drugs should also be monitored as orlistat may affect absorption.

Price Comparison: Why Choose Generic Orlistat

Generic orlistat offers significant savings over branded Xenical. A 4-week supply (84 capsules) costs £32.99 for orlistat vs £42.99 for Xenical. With code EDM10, you'll pay £29.69 for orlistat compared to £38.69 for Xenical - saving £9 per month. For a 12-week supply, choose orlistat at £86.39 vs Xenical at £116.09 (with EDM10), saving £29.70.

Clinical Effect: No Difference Between Products

Both orlistat and Xenical work by blocking approximately one third of dietary fat absorption. The lipase inhibitor mechanism is identical, providing the same weight management support when used alongside a reduced-calorie, lower-fat diet. Some patients prefer branded Xenical for reassurance, while others choose generic orlistat for value - the clinical outcome is the same.

Alternative: Alli 60mg Option

Alli 60mg offers half the dose of prescription-strength orlistat, potentially with milder side effects. At £26.09 for 4 weeks (with EDM10), it's positioned between the prescription options. However, the lower dose may be less effective for weight management compared to the 120mg prescription strength products.

How to Order Through EverydayMeds

Complete our online health questionnaire for clinical assessment by a UK-licensed prescriber. If orlistat or Xenical is deemed suitable, we'll dispense from our GPhC-registered pharmacy in Leicester with next day delivery. Both options require the same clinical assessment and have identical eligibility criteria. Use code EDM10 for 10% off your order.

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